Meta AnalysisID 7461
微量元素补充剂对中间疾病标志物的影响：随机对照试验的网状Meta分析
CRD42023422481
We analyzed changes in intermediate disease markers and conducted a systematic review and meta-analysis to clarify the role of trace elements on human body.
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7461
- Evidence Id
- 16019
- Core Evidence Id
- 16019
- Source Meta Analysis Id
- 7453
- Herb2 Meta Analysis Id
- HBMA007453
- Crd Id
- CRD42023422481
- Title
- Microelements supplements on intermediate-disease markers: a network meta-analysis of randomized controlled trials
- Review Question
- We analyzed changes in intermediate disease markers and conducted a systematic review and meta-analysis to clarify the role of trace elements on human body.
- Study Type Included
- Randomized controlled trials(RCTs) will be included.
- Condition Being Studied
- Globally, overweight and obesity have become an epidemic, both in adults and children, and the trend is increasing year by year and overweight have a higher risk of cardiovascular disease. Intermediate disease markers work in the human body, and it's changes can reflect the changes of some diseases in the human body , including cardiovascular disease. Trace elements are minerals that less than 0.01% of the human body weight , daily need is small, but essential to the human body. Among them, essential trace elements (such as iron, copper, zinc, selenium) play an important role in maintaining human normal metabolic. Imbalance of trace elements can cause multiple systems diseases, while there is controversy over their effects on human body. In view of the inconsistent reported in literatures, we analyzed changes in intermediate disease markers and conducted a systematic review and meta-analysis to clarify the role of trace elements on human body.
- Participant
- people with a mean age >18y
- Animal
- Human Disease Modelled
- Intervention
- Trace elements was the main intervention(e.g. Zinc, Chromium, Selenium)
- Comparator Control
- placebo treatment.
- Main Outcome
- LDL cholesterol, HDL cholesterol, Fasting blood glucose(FBG), tri-acylglycerol (TG), total cholesterol (TC).
- Outcome Measure
- Additional Outcome
- HOMA-IR, insulin，systolic and diastolic blood pressure (SBP/DBP), glycated hemoglobin (HbA1c), C-reactive protein (CRP), hypersensitiv e C-reactive protein(hs-CRP) and hemoglobin(Hb).
- Study Method
- Network meta-analysis, Systematic review
- Keyword
- Dietary Supplements; Human Body; Humans; Network Meta-Analysis; Randomized Controlled Trials as Topic; Trace Elements
- Contact
- linling Lu [email protected]
- Organisational Affiliation
- Yuebei People's Hospital
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-05-09
- Registration Date
- 2023-05-20
- Anticipated Start Date
- 2023-05-29
- Anticipated Completion Date
- 2023-07-05
- Title Cn
- 微量元素补充剂对中间疾病标志物的影响：随机对照试验的网状Meta分析
- Title En
- Microelements supplements on intermediate-disease markers: a network meta-analysis of randomized controlled trials
- Bilingual Status
- complete