Meta AnalysisID 7455
营养补充剂对代谢综合征成人脂肪因子、氧化应激和炎症标志物的比较效果：随机对照试验的网状Meta分析
CRD42023417473
Evidence from previous pairwise meta-analyses suggests that some nutritional supplements exert beneficial health effects, improving adipokine disorders, indicators of inflammation and oxidative stress. With regard to the
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7455
- Evidence Id
- 16013
- Core Evidence Id
- 16013
- Source Meta Analysis Id
- 7447
- Herb2 Meta Analysis Id
- HBMA007447
- Crd Id
- CRD42023417473
- Title
- Comparative effects of nutritional supplements on adipokines, oxidative stress and inflammatory markers in adults with metabolic syndrome: a network meta-analysis of randomized controlled trials
- Review Question
- Evidence from previous pairwise meta-analyses suggests that some nutritional supplements exert beneficial health effects, improving adipokine disorders, indicators of inflammation and oxidative stress. With regard to their comparative effects, however, uncertainties remain and have not been well ascertained, and the quality of the evidence needs to be further estimated.
- Study Type Included
- Randomized controlled trials
- Condition Being Studied
- Metabolic syndrome(including hypertension, hyperglycemia, hyperlipidemia, obesity, insulin resistance)
- Participant
- Adults with metabolic syndrome (age >=18 years)
- Animal
- Human Disease Modelled
- Intervention
- 1、vitamin and mineral supplements：chromium, selenium, zinc, coenzyme Q10 (CoQ10), α-Lipoic acid (ALA), Vitamin D, vitamin E, etc. 2、other supplements：n-3 polyunsaturated fatty acids(N-3 PUFAs), resveratrol, L-carnitine, tea / tea extract, garlic, synbiotics/probiotics, curcumin/turmeric, cinnamon, dietary anthocyanins, etc.
- Comparator Control
- Placebo or no treatment.
- Main Outcome
- 1、Adipokines Levels——visfatin、adiponectin、adipsin、leptin、resistin 2、oxidative stress ——total antioxidant capacity (TAC)、malondialdehyde(MDA) 、glutathione、superoxide dismutase (SOD) 、 3、inflammatory markers——C-reactive protein(CRP), tumour necrosis factorα(TNF-α)、interleukin-6(IL-6)、interleukin 1 beta(IL-1β) Measures of effect Weight mean difference
- Outcome Measure
- Additional Outcome
- None Measures of effect None
- Study Method
- Network meta-analysis, Systematic review
- Keyword
- Adipokines; Adult; Humans; Inflammation; Metabolic Syndrome; Oxidative Stress; Randomized Controlled Trials as Topic
- Contact
- Gongquan Wang [email protected]
- Organisational Affiliation
- Jilin University
- Funding Source
- This article is supported by "National Natural Science Foundation of China" (No.81900384) and "Natural Science Foundation of Jilin Province" (YDZJ202201ZYTS036). Grant number(s) State the funder, grant or award number and the date of award "National Natural Science Foundation of China" (No.81900384) and "Natural Science Foundation of Jilin Province" (YDZJ202201ZYTS036)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-04-15
- Registration Date
- 2023-04-26
- Anticipated Start Date
- 2023-05-01
- Anticipated Completion Date
- 2023-08-31
- Title Cn
- 营养补充剂对代谢综合征成人脂肪因子、氧化应激和炎症标志物的比较效果：随机对照试验的网状Meta分析
- Title En
- Comparative effects of nutritional supplements on adipokines, oxidative stress and inflammatory markers in adults with metabolic syndrome: a network meta-analysis of randomized controlled trials
- Bilingual Status
- complete