Meta AnalysisID 7447
刃厚皮片移植供皮区敷料的网状Meta分析：再上皮化时间与并发症
CRD42023449798
Population: Male and female patients undergoing Split-thickness skin graft harvest Intervention: Any type of topical dressing Comparison: control, placebo, or other type of dressing Outcome: Re-epithalization time or tim
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7447
- Evidence Id
- 16005
- Core Evidence Id
- 16005
- Source Meta Analysis Id
- 7440
- Herb2 Meta Analysis Id
- HBMA007440
- Crd Id
- CRD42023449798
- Title
- A Network Meta-Analysis of Split-Thickness Skin Graft Donor-Site Dressing: Re-Epithalization Time and Complication
- Review Question
- Population: Male and female patients undergoing Split-thickness skin graft harvest Intervention: Any type of topical dressing Comparison: control, placebo, or other type of dressing Outcome: Re-epithalization time or time to complete healing
- Study Type Included
- Inclusion Criteria: Studies published without time frame limitations up to August 2023. Published in English language. Reported Randomized Controlled trials (RCT) Patients undergone split-thickness skin graft harveste and donor-site managed by any dressing Reported outcomes of interest for the clinical question (full-healing time or Re-epithelization Time) Exclusion Criteria: Published in languages other than English. Improper method (Reported Pilot RCT, RCT protocol, a meta-analysis/systematic review, economic analysis, animal study, cadaver study, narrative review, editorial, non-randomized clinical trials, case series, or case report) Flap or full-thickness skin graft donor site. Used injectable, physiotherapy, cell suspension, biologic dressing, or anything other than dressing in the donor-site to promote healing Reported no outcomes of interest (Full-healing time or Re-epithalization Time) Unfound full-text
- Condition Being Studied
- Over 160, 000 skin grafts are conducted annually in approximately one out of every three burn hospitalizations, according to the Healthcare Cost and Utilization Project. If appropriate donor tissue and a healthy recipient bed are available, their utilization is prevalent since they are primarily simple and quick. (1) Split-thickness skin grafts (STSG) are widely used in reconstructive procedures and are known to cover wounds which are often caused by burns, abrasions, trauma, diseases, infections and etc. (2-3) The donor site dressings are usually easily to apply and should ideally lessen patient discomfort, reduce wound exudate leakage, and encourage re-epithelization within a course of 7-10 days. (4) Once STSG are harvested, the epidermal and dermal layers of skin at the donor site are damaged, leaving induced wound remains at the donor site. Therefore, after extracting a split-thickness skin graft, maintaining the integrity of the donor site is crucial since patients frequently experience more pain there than at the recipient site. Hence, leading to lengthier hospital stay, increased use of analgesics and overall delay in recovery and mobilization.(5)
- Participant
- Male and female patients undergoing Split-thickness skin graft harvest managed by topical dressing
- Animal
- Human Disease Modelled
- Intervention
- Any type of topical dressing. Including: (hydrocolloid OR silicone OR alginate OR hydrogel OR honey OR paraffin OR silver OR absorbent OR cellulose OR subcategories of those)
- Comparator Control
- control, placebo, or other type of dressing
- Main Outcome
- Re-epithalization time or time to complete healing Local Complications (Infection Rate, Pathologic scar).
- Outcome Measure
- Additional Outcome
- Level of evidence Age Gender Country Co-morbidity (DM) Reason of graft harvest (Receipiant-site) Graft Size Hx of pathologic scar (Hypertrophic or keloid) Type of Dressing Frequency of dressing change Side effect to dressing (Allergies) Pain score
- Study Method
- Cost effectiveness, Network meta-analysis, Systematic review
- Keyword
- Bandages; Female; Humans; Male; Men; Skin Transplantation; Wound Healing
- Contact
- Nawaf Alhindi [email protected]
- Organisational Affiliation
- KAU
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Saudi Arabia
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-07-29
- Registration Date
- 2023-08-10
- Anticipated Start Date
- 2023-07-29
- Anticipated Completion Date
- 2024-12-31
- Title Cn
- 刃厚皮片移植供皮区敷料的网状Meta分析：再上皮化时间与并发症
- Title En
- A Network Meta-Analysis of Split-Thickness Skin Graft Donor-Site Dressing: Re-Epithalization Time and Complication
- Bilingual Status
- complete