Meta AnalysisID 7394

磷酸钙基移植物联合引导组织再生治疗牙周组织缺损

CRD42023438450

What are the benefits of calcium phosphate-based grafts with GTR (intervention) over OFD alone (control) and its effect on periodontal regenerative parameters (outcome) such as clinical attachment level (CAL) and probing

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Record Fields

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Meta Analysis Id
7394
Evidence Id
15952
Core Evidence Id
15952
Source Meta Analysis Id
7384
Herb2 Meta Analysis Id
HBMA007384
Crd Id
CRD42023438450
Title
Calcium phosphate-based grafts combined with guided tissue regeneration in the treatment of periodontal tissue defects
Review Question
What are the benefits of calcium phosphate-based grafts with GTR (intervention) over OFD alone (control) and its effect on periodontal regenerative parameters (outcome) such as clinical attachment level (CAL) and probing pocket depth (PPD)
Study Type Included
RCTs
Condition Being Studied
Progressive periodontitis is a severe form of periodontal disease that can cause damage to the tissues and bones that support the teeth. If left untreated, it can lead to tooth loss due to the destruction of the attachment apparatus. The primary goals of periodontal therapy are to access the diseased areas, reduce pocket depth, stop the disease from getting worse, and restore lost periodontal tissue. The ultimate objective is to regenerate the periodontal and create a new attachment.
Participant
Chronic or aggressive periodontitis with no systemic diseases that contraindicated periodontal surgery
Animal
Human Disease Modelled
Intervention
Calcium phosphate(CPs) based grafts+guided tissue regeneration(GTR)
Comparator Control
Open flap deberdiment(OFD)
Main Outcome
Clinical attachment level (CAL) and Probing pocket depth (PPD)
Outcome Measure
Additional Outcome
Gingival scores(GI) Plaque scores(PL)
Study Method
Meta-analysis, Systematic review
Keyword
Calcium Phosphates; Guided Tissue Regeneration; Humans; calcium phosphate
Contact
Monireh Kouhi [email protected]
Organisational Affiliation
Isfahan University of Medical Sciences
Funding Source
Isfahan University of Medical Science
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Iran
Review Stage
Review Ongoing
First Submission Date
2023-06-21
Registration Date
2023-07-02
Anticipated Start Date
2022-05-01
Anticipated Completion Date
2023-09-20
Title Cn
磷酸钙基移植物联合引导组织再生治疗牙周组织缺损
Title En
Calcium phosphate-based grafts combined with guided tissue regeneration in the treatment of periodontal tissue defects
Bilingual Status
complete