Meta AnalysisID 7358
大豆异黄酮治疗代谢综合征核心特征：系统评价
CRD42023407110
How do soy isoflavones impact on patients with metabolic syndrome central features compared to standard treatment approaches?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7358
- Evidence Id
- 15916
- Core Evidence Id
- 15916
- Source Meta Analysis Id
- 7345
- Herb2 Meta Analysis Id
- HBMA007345
- Crd Id
- CRD42023407110
- Title
- Soy isoflavones as treatment of metabolic syndrome central features: A systematic review
- Review Question
- How do soy isoflavones impact on patients with metabolic syndrome central features compared to standard treatment approaches?
- Study Type Included
- We will include clinical trials to assess the effects of the treatment of metabolic syndrome components with soy isoflavones.
- Condition Being Studied
- Central features of metabolic syndrome (MetS).
- Participant
- Inclusion: patients with one or more components of metabolic syndrome treated by soy isoflavones (MetS diagnosed using recognised diagnostic criteria as the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III), International Diabetes Foundation (IDF), European Group for the Study of Insulin Resistance (EGIR), and World Health Organization (WHO)). Exclusion: other treatments different than soy isoflavones.
- Animal
- Human Disease Modelled
- Intervention
- Soy isoflavones, Phytoestrogens, Isoflavones, Soy Foods, Soybeans, Soy isoflavone glycosides, Genistin, Daidzin, Glycitin, Soy isoflavones aglycones, Genistein, Daidzein, Glycitein, Coumestrol, Pterocarpans, Rotenone.
- Comparator Control
- Lifestyle changes: healthy eating, physical activity, exercise, Heart-healthy eating, DASH (Dietary Approaches to Stop Hypertension), Losing weight, Improve emotional health, Quit smoking, Get enough good quality sleep, Calorie-restricted diets, lower-calorie diet, Intermittent fasting, N-3 polyunsaturated fat, Very low fat diet, Reduce intake of mono- and disaccharides, Replace saturated fat with mono- or polyunsaturated fat, Address secondary factors, Avoid refined carbohydrates, reduce total amount of dietary carbohydrate, Avoid alcohol, Monitoring blood sugar, Emotional support, Low salt and sodium diet, Drink less caffeine, Manage stress. Medicines: Angiotensin-converting enzyme (ACE) inhibitors, Angiotensin-2 receptor blockers (ARBs), diuretics, beta blockers, statins, niacin, omega fatty acids, Fibric Acid Derivatives, Fibrates, Metformin, Sulphonylureas, Glucagon-like peptide-1 (GLP-1) receptor agonists, Meglitinides, Alpha-Glucosidase, Inhibitors Thiazolidinediones, DPP- 4 Inhibitors, Biguanides, Dopamine Receptor Agonists, Bile Acid Sequestrants, SGLT2 Inhibitors, Amylin Analog, Insulin, Calcium channel blocker, Weight-loss medicines. Weight-loss surgery: Bariatric surgery. Weight-loss devices: Electrical stimulation system, Gastric balloon system, Gastric emptying system. Herbal remedies and dietary supplements.
- Main Outcome
- Improvement in the values of the MetS variables (Waist circumference, Triglycerides, High-density lipoprotein cholesterol (HDL), Fasting glucose, Blood pressure, and Microalbuminuria). Measures of effect Change from baseline
- Outcome Measure
- Additional Outcome
- HOMA-IR homeostatic model assessment of insulin resistance; insulin concentration; BMI: body mass index; lipid profile; C reactive protein; uric acid; resistin; resistin/uric acid index, metabolic endotoxemia. Measures of effect Change from baseline
- Study Method
- Intervention, Prevention, Systematic review
- Keyword
- Humans; Isoflavones; Ketones; Metabolic Syndrome; Patients; Soybeans
- Contact
- Vanessa Garcia-Rojas [email protected]
- Organisational Affiliation
- Instituto Politécnico Nacional (IPN)
- Funding Source
- Funding provided by sep-concacyt.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- After a search on the PROSPERO platform, no articles in progress on the same subject were found.
- Published Protocol
- Review Type
- Language
- English
- Country
- Mexico
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-04-04
- Registration Date
- 2023-04-15
- Anticipated Start Date
- 2023-05-01
- Anticipated Completion Date
- 2023-08-31
- Title Cn
- 大豆异黄酮治疗代谢综合征核心特征：系统评价
- Title En
- Soy isoflavones as treatment of metabolic syndrome central features: A systematic review
- Bilingual Status
- complete