Meta AnalysisID 7349
补充肌酸、左卡尼汀、β-丙氨酸或咖啡因对受训成年人力量和耐力提升的效果：系统评价与Meta分析
CRD42023457796
What are the effects of Creatine, L-carnitine, Beta-alanine and caffeine supplementation on specific conditional physical abilities in trained adults?
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Record Fields
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- Meta Analysis Id
- 7349
- Evidence Id
- 15907
- Core Evidence Id
- 15907
- Source Meta Analysis Id
- 7336
- Herb2 Meta Analysis Id
- HBMA007336
- Crd Id
- CRD42023457796
- Title
- Effects of the consumption of Creatine, L-Carnitine, Beta-alanine or Caffeine as means for the increase of strength and resistance in trained adults. Systematica review and meta-analysis
- Review Question
- What are the effects of Creatine, L-carnitine, Beta-alanine and caffeine supplementation on specific conditional physical abilities in trained adults?
- Study Type Included
- following the Cochrane systematic review handbook recommendations, part 2 chapter 3.3. Due to the feasibility of the interventions of interest, randomized clinical trials will be taken into account as a mandatory type of study, as this type of study allows preventing systematic differences between the initial characteristics of the participants investigated in different intervention groups in terms of factors. of confusion known and unknown.
- Condition Being Studied
- To approach a synthesis of the current scientific evidence on the effects of the consumption of Creatine, L-Carnitine, Beta-alanine and Caffeine in the increase of strength and endurance, a detailed physiological support is required, which allows to demonstrate contributions in the generalized use of supplements as a means to develop physical capacities in the benefited population, who intend to improve vitality and body functionality through supplementation, thus addressing the field of physical activity nutrition.
- Participant
- The included population criteria were determinate in accordance the chapter 3.2 instructions of Cochrane systematic review handbook. define in advanced the legibility criteria for the population as an mandatory step. Population: Human. Adults: male & female Inclusion criteria: adults over 18 years old and younger than 60 years old.physically active participants.relevant injuries free. any kind of physical activity participants. Exclusion criteria: Studies whose population presents the following comorbidities: diabetes, obesity, coronary disease, metabolic disease, or another disease that affects physical performance. Those inclusion criteria are justify because the main objective is to identify the effects in fully developed people who ingest these substances as a nutritional supplement in search of generating changes in their physical abilities and not as a treatment for possible diseases that affect their functionality and quality of life.
- Animal
- Human Disease Modelled
- Intervention
- Clinical trial studies evaluating supplementation interventions with Creatine, L-carnitine, Beta -alanine and caffeine. Inclusion criteria: studies where the core idea were determine the influence of one or many of those interventions as in the physical performance analyzing the effects in intermediate term. Exclusion criteria: studies with energy drink interventions, mixed supplementation with substances other than the mentioned interventions.
- Comparator Control
- Studies comparing interventions performed with a placebo.
- Main Outcome
- The core domains of outcomes are two. -Strength: knowing as a physically ability potentially developed with exercise and physical activity rated under specific condition to determinate the muscle skeletal system condition and functionality. Based on the many ways to measure this outcome the protocol specify the following measurement methods as the Cochrane systematic review handbook recommends on this cases. in chapter 3.2.4 There is not a system for identifying and grouping these outcome (already checked in the recommended data bases COMET and ICHOM). Therefore it is specified the measurement methods and time point to strength outcome. power, max strength, jump test, and resistance. analyzing 4 weeks or more of intervention effects only -Endurance: understanding it as other physical ability to show the oxygen metabolic pathway when the activity is for a long time (more then 10 minutes). The same logic was applied on this outcome therefore the measurement methods and time point determinate are. Vo2 MAX, long endurance tests, and aerobic trials. including 4 weeks intervention effects only too. Measures of effect The relative risk and odds ratios are both include in the measures effects following the Cochrane Systematic reviews guides
- Outcome Measure
- Additional Outcome
- Not applicable Measures of effect Not Applicable
- Study Method
- Meta-analysis, Network meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Carlos Torres [email protected]
- Organisational Affiliation
- National University of Colombia https://unal.edu.co/
- Funding Source
- National University of Colombia Grant number(s) State the funder, grant or award number and the date of award Physiological sciences department, 06/29/2023
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Colombia
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-20
- Registration Date
- 2023-10-02
- Anticipated Start Date
- 2023-09-14
- Anticipated Completion Date
- 2024-01-08
- Title Cn
- 补充肌酸、左卡尼汀、β-丙氨酸或咖啡因对受训成年人力量和耐力提升的效果：系统评价与Meta分析
- Title En
- Effects of the consumption of Creatine, L-Carnitine, Beta-alanine or Caffeine as means for the increase of strength and resistance in trained adults. Systematica review and meta-analysis
- Bilingual Status
- complete