Meta AnalysisID 7326
近视控制停止后会发生什么？停用阿托品后近视进展的系统评价与Meta分析
CRD42023463093
What are the consequences of discontinuing atropine-based myopia control treatment, regardless of the reason, such as atropine, or combination therapies involving atropine.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7326
- Evidence Id
- 15884
- Core Evidence Id
- 15884
- Source Meta Analysis Id
- 7314
- Herb2 Meta Analysis Id
- HBMA007314
- Crd Id
- CRD42023463093
- Title
- What Happens When Myopia Control Stops? A Systematic Review and Meta-Analysis of Myopia Progression after Cessation of Atropine
- Review Question
- What are the consequences of discontinuing atropine-based myopia control treatment, regardless of the reason, such as atropine, or combination therapies involving atropine.
- Study Type Included
- Randomized controlled trials(RCTs), Pseudo-RCTs, cohort and case-control studies.
- Condition Being Studied
- Myopia represents a significant and escalating public health issue, particularly in East Asia, where it has reached a pandemic level. By the year 2020, approximately 2.5 billion individuals are projected to be impacted by myopia. While various treatment methods have shown effectiveness, the presence of a rebound effect following therapy raises concerns about the true benefits of each treatment approach.
- Participant
- Inclusion criteria: - Studies with data associated with axial length or refractive error measurement - Studies enrolled participants with myopia who received the atropine-based myopia treatment for at least six months and then ceased the intervention more than 1 month - Patients who discontinue myopia control treatments, regardless of the reason, with no restriction to the age Exclusion criteria: - Case report, case series - Studies that involved participants with congenital or severe ophthalmological conditions or surgical history that may influence the outcome - Studies with overlapping participants
- Animal
- Human Disease Modelled
- Intervention
- Topical atropine or combination therapy involving atropine
- Comparator Control
- Placebo or non-myopia control devices such as spectacles or single vision contact lenses will be incorporated for comparative analysis
- Main Outcome
- Axial length Spherical equivalent Adherence and reasons of cessation Measures of effect After cessation 6 months, 12 months, 24 months, 36 months
- Outcome Measure
- Additional Outcome
- Nil
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- 7-methylxanthine; Atropine; Humans; Myopia; Xanthines
- Contact
- Ssu-Hsien Lee [email protected]
- Organisational Affiliation
- Buddist Hualian Tzu chi medical foundation
- Funding Source
- Nil
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Taiwan
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-12
- Registration Date
- 2023-09-23
- Anticipated Start Date
- 2023-09-12
- Anticipated Completion Date
- 2023-10-20
- Title Cn
- 近视控制停止后会发生什么？停用阿托品后近视进展的系统评价与Meta分析
- Title En
- What Happens When Myopia Control Stops? A Systematic Review and Meta-Analysis of Myopia Progression after Cessation of Atropine
- Bilingual Status
- complete