Meta AnalysisID 7302
砷与不良妊娠结局/宫内生长受限的关联：系统评价与Meta分析
CRD42023473902
Effects of arsenic exposure during pregnancy on pregnancy outcomes:A systematic review and meta-analysis
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7302
- Evidence Id
- 15860
- Core Evidence Id
- 15860
- Source Meta Analysis Id
- 7290
- Herb2 Meta Analysis Id
- HBMA007290
- Crd Id
- CRD42023473902
- Title
- Association of arsenic with adverse pregnancy outcomes/intrauterine growth restriction: A systematic review and meta-analysis
- Review Question
- Effects of arsenic exposure during pregnancy on pregnancy outcomes:A systematic review and meta-analysis
- Study Type Included
- Subjects must be women and female rats exposed (by any means) to arsenic and arsenic compounds (As, As2O3, As2O5) during pregnancy (at any stage). Inclusion criteria: (1) Outcome measures included low birth weight (BW<2500g), (2) Small for gestational age or intrauterine growth restriction. The exclusion criteria for literatures are as follows: (1) Literatures with sample size less than 30 should be excluded; (2) Literature from population epidemiological investigations, including retrospective or prospective cohort studies and case-control studies, should be excluded if the study subjects have been observed for more than 1 year; (3) Review literature is also excluded.
- Condition Being Studied
- Arsenic (As), a highly toxic metal-like element that is widely present in the Earth's environment, has been shown to easily cross the placental barriers of humans and animals. Due to changes in physiological status, maternal metabolism is strong, so exposure to arsenic environment is more likely to increase the risk of adverse pregnancy outcomes. At present, a considerable number of studies at home and abroad have focused on the effects of arsenic on human health, but there are few literatures focusing on the characteristics of arsenic exposure in pregnant women.
- Participant
- Subjects must be women and female rats exposed (by any means) to arsenic and arsenic compounds (As, As2O3, As2O5) during pregnancy (at any stage). Inclusion criteria: (1) Outcome measures included low birth weight (BW<2500g), (2) Small for gestational age or intrauterine growth restriction. The exclusion criteria for literatures are as follows: (1) Literatures with sample size less than 30 should be excluded; (2) Literature from population epidemiological investigations, including retrospective or prospective cohort studies and case-control studies, should be excluded if the study subjects have been observed for more than 1 year; (3) Review literature is also excluded.
- Animal
- Human Disease Modelled
- Intervention
- Must be women and female rats exposed (by any means) to arsenic and arsenic compounds (As, As2O3, As2O5) during pregnancy (any stage)
- Comparator Control
- Normal pregnancy
- Main Outcome
- Outcome indicators: Adverse pregnancy outcome, pregnancy outcome, low birth weight, small for gestational age, intrauterine growth retardation, intrauterine growth retardation, intrauterine growth retardation.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Jing Jiang [email protected]
- Organisational Affiliation
- School of Public Health, Zunyi Medical University
- Funding Source
- This work was supported by Nature Science Foundation of Guizhou Provincial (QKH-J[2022]YB612), National Key R&D Program of China (2018YFC1004302), Science & Technology Program of Guizhou Province, China (QKHHBZ [2020]3002), City School Joint Foundation Project (ZYKH-HZ-Z[2021]292)，City School Joint Foundation Project (QKH-PTRC[2019]-003 )，Start-up Foundation for Doctors of Zunyi Medical University (QKH-PTRC[2019]-032).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-10-18
- Registration Date
- 2023-10-29
- Anticipated Start Date
- 2023-10-18
- Anticipated Completion Date
- 2024-06-18
- Title Cn
- 砷与不良妊娠结局/宫内生长受限的关联：系统评价与Meta分析
- Title En
- Association of arsenic with adverse pregnancy outcomes/intrauterine growth restriction: A systematic review and meta-analysis
- Bilingual Status
- complete