Meta AnalysisID 7300
基于Meta分析的砷暴露与黑色素瘤关系评估
CRD42023460432
The purpose of this systematic review is to answer the following question : Is there an association between arsenic exposure and melanoma incidence? The PICO search strategy(p=population, I=intervention, C=comparison and
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7300
- Evidence Id
- 15858
- Core Evidence Id
- 15858
- Source Meta Analysis Id
- 7288
- Herb2 Meta Analysis Id
- HBMA007288
- Crd Id
- CRD42023460432
- Title
- A Meta-analysis-based Assessment of the Relationship between Arsenic Exposure and Melanoma
- Review Question
- The purpose of this systematic review is to answer the following question : Is there an association between arsenic exposure and melanoma incidence? The PICO search strategy(p=population, I=intervention, C=comparison and O=outcomes) was used to define the four main components of the research question as follows:P=Adults >18 years , I=Arsenic exposure, C=non-Arsenic exposure, and O=Melanoma occurs with or without
- Study Type Included
- The types of studies we will include were Case-control study、Prospective cohort study or interventional studies/clinical trials.
- Condition Being Studied
- Melanoma is a tumor that comes from the malignant transformation of melanocytes, and the degree of malignancy is extremely high. It can be found in all age groups, with higher incidence in middle and old age, and the incidence rate is increasing gradually with high growth rate every year, and it has become one of the tumors with the fastest growing incidence rate, and the earlier it is found, the better the treatment effect will be. At present, ultraviolet irradiation is the main risk factor of melanoma, but there are still many other risk factors, such as arsenic, petrochemicals, etc., and the relationship between the above mentioned factors and melanoma has not yet been supported by sufficient evidences. The relationship between these factors and melanoma has not been supported by sufficient evidence.
- Participant
- Inclusion: Observational studies (cohort studies, case-control, excluding cross-sectional studies), interventional studies/clinical trials Exclusion: Unable to determine if exposure occurred prior to melanoma Studies which included children Duplicate cohorts (the most complete and/or most recent study will be selected) Participants/population: Adults >18 years of age
- Animal
- Human Disease Modelled
- Intervention
- Arsenic exposure
- Comparator Control
- Adults without arsenic exposure
- Main Outcome
- Incident melanoma Measures of effect Risk ratio and 95 percent confidence interval were used
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adult; Humans; Incidence; Melanoma; Syndrome
- Contact
- Wenlong Shuai [email protected]
- Organisational Affiliation
- the north of sichuan medical college
- Funding Source
- no
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-04
- Registration Date
- 2023-09-15
- Anticipated Start Date
- 2023-08-15
- Anticipated Completion Date
- 2024-03-31
- Title Cn
- 基于Meta分析的砷暴露与黑色素瘤关系评估
- Title En
- A Meta-analysis-based Assessment of the Relationship between Arsenic Exposure and Melanoma
- Bilingual Status
- complete