Meta AnalysisID 7248

α-硫辛酸对血压的影响:随机临床试验的系统评价与剂量-反应Meta分析

CRD42023447658

1. Is there any association between Alpha lipoic acid supplementation and systolic blood pressure (SBP)? 2. Is there any association between Alpha lipoic acid supplementation and diastolic blood pressure (DBP)?

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Record Fields

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Meta Analysis Id
7248
Evidence Id
15806
Core Evidence Id
15806
Source Meta Analysis Id
7232
Herb2 Meta Analysis Id
HBMA007232
Crd Id
CRD42023447658
Title
The effect of Alpha lipoic acid (ALA) on blood pressure: A systematic review and dose-response meta-analysis ofrandomized clinical trials
Review Question
1. Is there any association between Alpha lipoic acid supplementation and systolic blood pressure (SBP)? 2. Is there any association between Alpha lipoic acid supplementation and diastolic blood pressure (DBP)?
Study Type Included
Randomized placebo-controlled trials (either crossover or parallel design)
Condition Being Studied
Healthy, overweight or obese individuals, and those with any metabolic non-communicable disease such ascardiovascular disorders, dyslipidemia, hypercholesterolemia, metabolic syndrome
Participant
Adults over 18 years of age.
Animal
Human Disease Modelled
Intervention
Alpha lipoic acid supplementation
Comparator Control
Control group receiving a placebo
Main Outcome
Systolic blood pressure (SBP) and diastolic blood pressure (DBP) Measures of effect The time and effect measure will be done by dose-response assessment of the effects of Alpha lipoic acid according to dose and duration.
Outcome Measure
Additional Outcome
Weight and BMI
Study Method
Meta-analysis, Systematic review
Keyword
Blood Pressure; Dietary Supplements; Humans; Hypertension; Thioctic Acid; Vital Signs
Contact
Mahdi Vajdi [email protected]
Organisational Affiliation
Isfahan University of Medical Sciences, Isfahan, Iran.
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Iran
Review Stage
Review Ongoing
First Submission Date
2023-07-22
Registration Date
2023-08-02
Anticipated Start Date
2023-07-20
Anticipated Completion Date
2024-01-01
Title Cn
α-硫辛酸对血压的影响:随机临床试验的系统评价与剂量-反应Meta分析
Title En
The effect of Alpha lipoic acid (ALA) on blood pressure: A systematic review and dose-response meta-analysis ofrandomized clinical trials
Bilingual Status
complete