Meta AnalysisID 7244
植物性物质和营养补充剂治疗对成人患者耳鸣严重程度感知影响的系统评价与Meta分析
CRD42023446824
What evidence is there about the effectiveness of herbal therapy or nutritional supplements compared to placebo or concomitan interventions in reducing the severity of tinnitus in adults with acute or chronic tinnitus?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7244
- Evidence Id
- 15802
- Core Evidence Id
- 15802
- Source Meta Analysis Id
- 7228
- Herb2 Meta Analysis Id
- HBMA007228
- Crd Id
- CRD42023446824
- Title
- A systematic review and meta-analysis of the effects of plant-based substances and nutritional supplements therapy on tinnitus severity perception in adult patients
- Review Question
- What evidence is there about the effectiveness of herbal therapy or nutritional supplements compared to placebo or concomitan interventions in reducing the severity of tinnitus in adults with acute or chronic tinnitus?
- Study Type Included
- Randomized clinical trials (RCTs) comparing the use of herbal compound or dietary supplements therapy versus placebo or any control group with a concomitant intervention on tinnitus patients.
- Condition Being Studied
- Tinnitus in adults with chronic or acute tinnitus through these domains: a) Tinnitus severity measured through subjective assessment of tinnitus severity, frequency or annoyance using visual analogue scales (VAS). b) Tinnitus loudness can be measured through performance-based procedures such as tinnitus loudness or pitch matching. c) The impact of tinnitus on patients’ daily life can be measured on standardized self-reported questionnaires.
- Participant
- Inclusion: The studies considered in the review will include adult patients with subjective tinnitus (acute or chronic) or participants with tinnitus due to (sudden) sensorineural hearing loss, regardless of sex. Exclusion: Will be excluded studies considering persons under 18 years, or whit other neurological disorder or cognitive impairment.
- Animal
- Human Disease Modelled
- Intervention
- Eligible interventions include herbal compounds (e.g., Ginkgo biloba, Açaí, Hangekobokuto, caffeine), dietary supplements (e.g., melatonin, alpha-lipoic acid, papaverine hydrochloride, manganese, zinc sulfate, vitamin B complex).
- Comparator Control
- Control group with placebo or concomitant interventions.
- Main Outcome
- Changes in the score of questionnaires, scales, clinical tests that evaluate the tinnitus severity. The results obtained will be combined in a meta-analysis. Measures of effect The primary outcome will be reported and analyzed as a standardized mean difference if such data is available: a) tinnitus subjective severity outcomes (e.g., frequency or annoyance using visual analogue scales (VAS)). b) tinnitus psychoacoustic outcomes (e.g., tinnitus loudness or pitch matching)
- Outcome Measure
- Additional Outcome
- Changes in the score of questionnaires, scales, clinical tests that evaluate impact of tinnitus on patients’ daily life. Measures of effect If available, additional outcomes will be reported and analyzed as a standardized mean difference.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adult; Dietary Supplements; Humans; Patients; Phytotherapy; Tinnitus
- Contact
- Yordanis Enriquez Canto [email protected]
- Organisational Affiliation
- Universidad Católica Sedes Sapientiae https://www.ucss.edu.pe/facultad-salud
- Funding Source
- No sponsors
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Chile, Peru
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-07-19
- Registration Date
- 2023-07-31
- Anticipated Start Date
- 2023-08-09
- Anticipated Completion Date
- 2023-11-09
- Title Cn
- 植物性物质和营养补充剂治疗对成人患者耳鸣严重程度感知影响的系统评价与Meta分析
- Title En
- A systematic review and meta-analysis of the effects of plant-based substances and nutritional supplements therapy on tinnitus severity perception in adult patients
- Bilingual Status
- complete