Meta AnalysisID 7217
醋酸治疗口腔颌面外科铜绿假单胞菌相关皮瓣感染的有效性
CRD42023437598
The efficacy of acetic acid in the management of pseudomonas aeruginosa related flap infection in oral & maxillofacial surgery
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7217
- Evidence Id
- 15775
- Core Evidence Id
- 15775
- Source Meta Analysis Id
- 7204
- Herb2 Meta Analysis Id
- HBMA007204
- Crd Id
- CRD42023437598
- Title
- The efficacy of acetic acid therapy in the management of pseudomonas aeruginosa related flap infection in oral & maxillofacial surgery
- Review Question
- The efficacy of acetic acid in the management of pseudomonas aeruginosa related flap infection in oral & maxillofacial surgery
- Study Type Included
- Inclusion criteria: 1. RCTs and case series investigating the efficacy of acetic acid therapy in the management of pseudomonas aeruginosa related flap infection in oral & maxillofacial surgery 2. English language 3. Human subjects Exclusion criteria: 1. Non-English 2. Case reports, abstracts, book chapters, oral/poster presentations 3. Papers where acetic acid therapy is not utilised
- Condition Being Studied
- Pseudomonas aeruginosa is an opportunistic pathogen with an innate resistance to many antibiotics & disinfectants. It is also considered by many as an important cause of nosocomial infections due to its ability to survive in the hospital environment. It has also been associated with an increase in hospital stay, an increase in cost, and also with high morbidity. Oral and maxillofacial surgical patients that have undergone free flap surgery are susceptible to such infections due to longer hospital stay. If flap recipient site becomes infected, the patient may be at an increased risk of return to theatre, infection of underlying metal-work (if present) and flap failure. This introduces a higher degree of morbidity to this patient cohort.
- Participant
- Patients: Oral and maxillofacial patients that have undergone free flap surgery and that have developed pseudomonas aeruginosa infection in the recipient site
- Animal
- Human Disease Modelled
- Intervention
- Acetic acid therapy
- Comparator Control
- Alternative management options of pseudomonas aeruginosa infected flaps, e.g. washout with betadine & saline, antibiotics, regular dressing changes
- Main Outcome
- 1. Clearance of pseudomonas aeruginosa infection Measures of effect Relative risk and odds ratio
- Outcome Measure
- Additional Outcome
- 1. Length of hospital stay in each treatment group 2. Number of times patients return to theatre 3. Flap failure 4. Number of washouts Measures of effect 1. Mean difference between treatment groups (with regards to length of hospital stay, return to theatre, and number of washouts) 2. Relative risk and odds risk for flap failure
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Acetic Acid; Humans; Pseudomonas aeruginosa; Surgical Flaps
- Contact
- Munir Abukhder [email protected]
- Organisational Affiliation
- University College London Hospital
- Funding Source
- No funding
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-06-18
- Registration Date
- 2023-06-20
- Anticipated Start Date
- 2023-06-25
- Anticipated Completion Date
- 2023-11-01
- Title Cn
- 醋酸治疗口腔颌面外科铜绿假单胞菌相关皮瓣感染的有效性
- Title En
- The efficacy of acetic acid therapy in the management of pseudomonas aeruginosa related flap infection in oral & maxillofacial surgery
- Bilingual Status
- complete