Meta AnalysisID 7211
皮质类固醇、透明质酸与富血小板血浆：是否存在临床相关差异？系统评价与Meta分析
CRD42023466155
The aim of this systematic review and meta-analysis was to quantify and compare the clinical effectiveness of intra-articular corticosteroids (CS), hyaluronic acid (HA), and platelet-rich plasma (PRP) in knee osteoarthri
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7211
- Evidence Id
- 15769
- Core Evidence Id
- 15769
- Source Meta Analysis Id
- 7198
- Herb2 Meta Analysis Id
- HBMA007198
- Crd Id
- CRD42023466155
- Title
- Corticosteroids, hyaluronic acid, and platelet-rich plasma: Is there a clinically relevant difference? A systematic review and meta-analysis.
- Review Question
- The aim of this systematic review and meta-analysis was to quantify and compare the clinical effectiveness of intra-articular corticosteroids (CS), hyaluronic acid (HA), and platelet-rich plasma (PRP) in knee osteoarthritis (OA) patients in terms of patient-reported outcome measures and Minimal Clinically Important Difference (MCID).
- Study Type Included
- The following inclusion criteria were used: RCTs, written in English language and with no time limitation, on intra-articular injections of CSs, HA, and PRP for the treatment of osteoarthritis.
- Condition Being Studied
- Knee osteoarthritis
- Participant
- Males and females with no age limitation affected by knee osteoarthritis
- Animal
- Human Disease Modelled
- Intervention
- Intra-articular knee injection of corticosteroids
- Comparator Control
- Intra-articular knee injection of hyaluronic acid or PRP
- Main Outcome
- The primary outcome of this meta-analysis was the overall Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score at mid-term follow-up (>3 months and ≤6 months).
- Outcome Measure
- Additional Outcome
- Secondary outcomes were overall WOMAC score very short- (≤6 weeks), short- (>6 weeks and ≤3 months), and long-term (>6 months and ≤12 months) follow-ups and pain measured on the visual analogue scale (VAS) at very short- (≤6 weeks), short- (>6 weeks and ≤3 months), mid- (>3 months and ≤6 months) and long-term (>6 months and ≤12 months) follow-ups.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Alessandro Bensa [email protected]
- Organisational Affiliation
- Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Switzerland
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-22
- Registration Date
- 2023-10-03
- Anticipated Start Date
- 2023-06-08
- Anticipated Completion Date
- 2023-12-31
- Title Cn
- 皮质类固醇、透明质酸与富血小板血浆：是否存在临床相关差异？系统评价与Meta分析
- Title En
- Corticosteroids, hyaluronic acid, and platelet-rich plasma: Is there a clinically relevant difference? A systematic review and meta-analysis.
- Bilingual Status
- complete