Meta AnalysisID 7204

早产儿疑似过渡性循环休克的治疗:系统评价、网状Meta分析及临床实践指南

CRD42023446535

In the management of a preterm neonate with probable transitional circulatory shock, what should be the preferred first-line vasopressor agent for improving neonatal outcomes?

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Record Fields

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Meta Analysis Id
7204
Evidence Id
15762
Core Evidence Id
15762
Source Meta Analysis Id
7191
Herb2 Meta Analysis Id
HBMA007191
Crd Id
CRD42023446535
Title
Treatment of preterm neonates with probable transitional circulatory shock: A systematic review, network meta-analysis and clinical practice guidelines.
Review Question
In the management of a preterm neonate with probable transitional circulatory shock, what should be the preferred first-line vasopressor agent for improving neonatal outcomes?
Study Type Included
Randomized Controlled trials
Condition Being Studied
Probable transitional circulatory shock (as defined by the author)
Participant
Preterm neonates < 37 weeks and of less than 72 hours of postnatal age with probable transitional circulatory shock (as defined by the author). If the mean or median postnatal age of the included neonates is less than 72 hours, those would also be included.
Animal
Human Disease Modelled
Intervention
Volume expansion, Dopamine, Dobutamine, Milrinone, Epinephrine, Norepinephrine, Vasopressin, Hydrocortisone, Volume expansion, Placebo
Comparator Control
Volume expansion, Dopamine, Dobutamine, Milrinone, Epinephrine, Norepinephrine, Vasopressin, Hydrocortisone, Volume expansion, Placebo
Main Outcome
Mortality until discharge Severe brain injury (Severe Intraventricular Haemorrhage> grade 2 or Cystic Periventricular Leukomalacia) Measures of effect Relative risks (RR) with 95% Credible Interval (CrI)
Outcome Measure
Additional Outcome
Necrotising enterocolitis ≥ Stage 2 Response to treatment (as defined by the author) Measures of effect Relative risks (RR) with 95% Credible Interval (CrI)
Study Method
Network meta-analysis, Systematic review
Keyword
Cardiovascular System; Humans; Infant, Newborn; Network Meta-Analysis; Shock; Vasoconstrictor Agents
Contact
Gunjana Kumar [email protected]
Organisational Affiliation
National Institute of Medical Sciences, Jaipur, Rajasthan
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
India
Review Stage
Review Ongoing
First Submission Date
2023-08-29
Registration Date
2023-09-09
Anticipated Start Date
2023-09-05
Anticipated Completion Date
2023-11-01
Title Cn
早产儿疑似过渡性循环休克的治疗:系统评价、网状Meta分析及临床实践指南
Title En
Treatment of preterm neonates with probable transitional circulatory shock: A systematic review, network meta-analysis and clinical practice guidelines.
Bilingual Status
complete