Meta AnalysisID 7201
类固醇是否能改善重度烧伤患者的结局？一项比较糖皮质激素与雄激素类固醇在烧伤损伤各阶段作用的系统评价
CRD42023437025
Do steroids improve outcomes for patients with severe burns? Comparison of the role of corticosteroids and androgenic steroids throughout the phases of burn injury
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7201
- Evidence Id
- 15759
- Core Evidence Id
- 15759
- Source Meta Analysis Id
- 7188
- Herb2 Meta Analysis Id
- HBMA007188
- Crd Id
- CRD42023437025
- Title
- Do steroids improve outcomes for patients with severe burns? A systematic review comparing the role of corticosteroids and androgenic steroids throughout the phases of burn injury
- Review Question
- Do steroids improve outcomes for patients with severe burns? Comparison of the role of corticosteroids and androgenic steroids throughout the phases of burn injury
- Study Type Included
- Randomised controlled trials, non-randomised controlled studies, observational studies.
- Condition Being Studied
- Severe burn injury. Burn shock; hypermetabolism following burn injury.
- Participant
- Inclusion: Adult and paediatric patients with severe burn injury, >20%TBSA or other indicator of severe burn (e.g., inhalation injury). Exclusion: minor burn injury, minor epidermal burns
- Animal
- Human Disease Modelled
- Intervention
- Intervention 1: corticosteroids, e.g., hydrocortisone Intervention 2: androgenic steroids, e.g., oxandrolone
- Comparator Control
- Placebo or normal treatment.
- Main Outcome
- Mortality
- Outcome Measure
- Additional Outcome
- Adverse events Length of stay in hospital/ICU Shock duration Vasopressor use Wound healing, graft failure
- Study Method
- Systematic review
- Keyword
- Adrenal Cortex Hormones; Burns; Humans; Patients; Steroids
- Contact
- Elizabeth Coady [email protected]
- Organisational Affiliation
- Concord Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney
- Funding Source
- Not applicable
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Australia
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-06-16
- Registration Date
- 2023-06-27
- Anticipated Start Date
- 2023-06-08
- Anticipated Completion Date
- 2023-11-30
- Title Cn
- 类固醇是否能改善重度烧伤患者的结局？一项比较糖皮质激素与雄激素类固醇在烧伤损伤各阶段作用的系统评价
- Title En
- Do steroids improve outcomes for patients with severe burns? A systematic review comparing the role of corticosteroids and androgenic steroids throughout the phases of burn injury
- Bilingual Status
- complete