Meta AnalysisID 7169

左甲状腺素治疗对甲状腺过氧化物酶抗体阳性且甲状腺功能正常的女性在孕前的应用:一项系统评价与Meta分析

CRD42023410414

Is levothyroxine treatment effective in TPOAb-positive euthyroid women?

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Record Fields

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Meta Analysis Id
7169
Evidence Id
15727
Core Evidence Id
15727
Source Meta Analysis Id
7156
Herb2 Meta Analysis Id
HBMA007156
Crd Id
CRD42023410414
Title
Levothyroxine treatment in TPOAb-positive euthyroid women before conception: a systematic review and meta-analysis
Review Question
Is levothyroxine treatment effective in TPOAb-positive euthyroid women?
Study Type Included
RCT and non-randomized controlled trials.
Condition Being Studied
Women positive for thyroid peroxidase antibodies (TPO-Ab) have an increased risk of pregnancy loss. However, treatment with levothyroxine in euthyroid women who are TPO-Ab positive remains controversial.
Participant
TPOAb-positive euthyroid women planning to conceive
Animal
Human Disease Modelled
Intervention
Levothyroxine
Comparator Control
placebo or no treatment
Main Outcome
Miscarriage and pregnancy rate.
Outcome Measure
Additional Outcome
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Female; Humans; Hypothyroidism; Thyrotropin; Thyroxine
Contact
Henrique Graf Provinciatto [email protected]
Organisational Affiliation
Barao de Maua University Center
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2023-03-22
Registration Date
2023-04-02
Anticipated Start Date
2023-03-23
Anticipated Completion Date
2023-05-23
Title Cn
左甲状腺素治疗对甲状腺过氧化物酶抗体阳性且甲状腺功能正常的女性在孕前的应用:一项系统评价与Meta分析
Title En
Levothyroxine treatment in TPOAb-positive euthyroid women before conception: a systematic review and meta-analysis
Bilingual Status
complete