Meta AnalysisID 7146
可持续蛋白质摄入对老年人群营养摄入、肠道健康及年龄相关健康的影响：系统评价和Meta分析方案
CRD42023459818
How does consumption of sustainable proteins compared to consumption of non-sustainable or meat-based proteins impact on nutrient intake, gut health and age-related changes in healthy, community-dwelling individuals aged
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7146
- Evidence Id
- 15704
- Core Evidence Id
- 15704
- Source Meta Analysis Id
- 7132
- Herb2 Meta Analysis Id
- HBMA007132
- Crd Id
- CRD42023459818
- Title
- The effect of sustainable protein consumption on nutrient intake, gut health and age-related health in an ageing population: Protocol of a systematic review and meta-analysis
- Review Question
- How does consumption of sustainable proteins compared to consumption of non-sustainable or meat-based proteins impact on nutrient intake, gut health and age-related changes in healthy, community-dwelling individuals aged 65 years or over.
- Study Type Included
- We will include randomized controlled trials (RCTs), including cluster RCTs, controlled (non-randomized) clinical trials (CCTs) or cluster trials, interrupted time series (ITS) studies with at least three data points before and after the intervention, controlled before-after (CBA) studies, prospective and retrospective comparative cohort studies, observational studies and case-control or nested case-control studies. Cluster randomized, cluster non-randomized, or CBA studies will be included only if there are at least two intervention sites and two control sites. We will exclude cross-sectional studies, case series, case reports and studies in animals.
- Condition Being Studied
- Sustainable diets and gut health in older age
- Participant
- Studies examining the general older adult human population or healthy older adult humans with an age of 65 years or older. Studies will also be included with people who are underweight, overweight or obese but we will otherwise exclude studies of populations restricted to specific diseases, conditions, or metabolic disorders. We will include studies addressing adults in general if data provided for older adults (>65 years) are reported separately.
- Animal
- Human Disease Modelled
- Intervention
- Increased consumption of sustainable proteins and diets in combination with any other nutrients. Interventions may include: supplementation with plant-based proteins, such as legumes or pulses, soy, wheat, or vegetables; supplementation with concentrated forms of plant protein; whole diet interventions such as vegetarian/vegan or a general healthy diet, high in sustainable protein or low in red meat with concomitant increase in sustainable protein or a diet higher in sustainable proteins (Mediterranean, vegetarian, plant-based). Exposures may include dietary educational resources or dietary public health policies or a populations habitual diet, which may have a natural higher or lower plant-based protein. Studies with other lifestyle components (i.e., physical activity) will only be included if dietary effects are reported separately. The minimum intervention or exposure period will be 2 weeks, which has been shown to be sufficient to improve the metabolic picture and reverse gut microbiota dysbiosis in older obese women.
- Comparator Control
- Older adults exposed to a low intake of sustainable or plant proteins or a high intake of animal proteins.
- Main Outcome
- • Nutrient intake: Energy; Carbohydrates with breakdown of sugars and dietary fibre; protein including types of amino acids and essential amino acids; total fat including saturated fat, monounsaturated fatty acids and polyunsaturated fatty acids; sodium; and vitamins and minerals. • Food Groups: Meats, fish and poultry; eggs; beans and pulses; milk and other dairy products; fruit and vegetables; breads, grains, potatoes and other starchy foods; oils, fats and spreads; sweets and snacks; and drink intake. • Gut microbiome: Measurement of microbiota and inflammation status. Outcomes will be extracted as reported, with the exception of quality of life, which will be collected only if assessed with generic (not disease specific), validated tools. Measures of effect Risk ratio and mean difference
- Outcome Measure
- Additional Outcome
- • Health: Age/age category, quality of life (validated tools only), muscle mass, muscle strength, physical performance/level or type of activity, pre-frailty, frailty, sarcopenia, weight category (i.e., underweight/obese), malnutrition, mortality. Measures of effect Risk ratio and mean difference
- Study Method
- Intervention, Meta-analysis, Prevention, Systematic review
- Keyword
- Aging; Eating; Energy Intake; Healthy Aging; Humans; Meat Proteins; Meta-Analysis as Topic; Systematic Reviews as Topic
- Contact
- Debra Jones [email protected]
- Organisational Affiliation
- University of Manchester www.manchester.ac.uk
- Funding Source
- Managed by University of Manchester, University of Glasgow and University of Cambridge
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-04
- Registration Date
- 2023-09-05
- Anticipated Start Date
- 2023-09-05
- Anticipated Completion Date
- 2023-12-22
- Title Cn
- 可持续蛋白质摄入对老年人群营养摄入、肠道健康及年龄相关健康的影响：系统评价和Meta分析方案
- Title En
- The effect of sustainable protein consumption on nutrient intake, gut health and age-related health in an ageing population: Protocol of a systematic review and meta-analysis
- Bilingual Status
- complete