Meta AnalysisID 7113
补充α-亚麻酸对超重或肥胖人群心血管风险谱影响的随机对照试验系统评价与Meta分析
CRD42023429563
This systematic review and meta-analysis aims to investigate the effects of supplementation with ALA on cardiovascular risk factors (i.e. inflammatory markers, blood pressure, and blood lipid profile) in individuals with
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7113
- Evidence Id
- 15671
- Core Evidence Id
- 15671
- Source Meta Analysis Id
- 7100
- Herb2 Meta Analysis Id
- HBMA007100
- Crd Id
- CRD42023429563
- Title
- Effect of alpha-linolenic acid supplementation on cardiovascular risk profile in individuals with overweight or obesity: A systematic review and meta-analysis of randomized controlled trials
- Review Question
- This systematic review and meta-analysis aims to investigate the effects of supplementation with ALA on cardiovascular risk factors (i.e. inflammatory markers, blood pressure, and blood lipid profile) in individuals with obesity or overweight.
- Study Type Included
- Randomized controlled trials with parallel or crossover design.
- Condition Being Studied
- Overweight or obesity
- Participant
- Individuals with obesity or overweight, excluded if participants pregnant women and nursing mothers and enteral or parenteral feeding.
- Animal
- Human Disease Modelled
- Intervention
- Dietary supplementation with ALA (including using flaxseed oil, chia seed, linseed, canola, rapeseed, walnut, perilla seed, or their derivates as sources of ALA).
- Comparator Control
- Placebo or control group.
- Main Outcome
- Primary outcomes of interest will be inflammatory markers (C-reactive protein, interleukin-6, tumor necrosis factor), blood pressure, and blood lipid profile (triglyceride, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol). Measures of effect Mean change and SD of outcomes of interest.
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Intervention, Meta-analysis, Prevention, Review of reviews, Systematic review
- Keyword
- Cardiovascular Diseases; Dietary Supplements; Humans; Lipids; Obesity; Overweight; Randomized Controlled Trials as Topic; Risk Factors; alpha-Linolenic Acid
- Contact
- Shiyu Yin [email protected]
- Organisational Affiliation
- Southeast Univertisy
- Funding Source
- This work was funded by National Natural Science Foundation of China. Grant number(s) State the funder, grant or award number and the date of award Grant No. 82173509
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-06-05
- Registration Date
- 2023-06-16
- Anticipated Start Date
- 2023-04-25
- Anticipated Completion Date
- 2023-07-05
- Title Cn
- 补充α-亚麻酸对超重或肥胖人群心血管风险谱影响的随机对照试验系统评价与Meta分析
- Title En
- Effect of alpha-linolenic acid supplementation on cardiovascular risk profile in individuals with overweight or obesity: A systematic review and meta-analysis of randomized controlled trials
- Bilingual Status
- complete