Meta AnalysisID 7110

膳食补充α-亚麻酸对血脂异常患者炎性生物标志物影响的随机对照试验系统评价与Meta分析

CRD42023413131

This systematic review and meta-analysis aims to investigate the effects of supplementation with ALA on inflammatory biomarker in individuals with dyslipidemias.

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Record Fields

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Meta Analysis Id
7110
Evidence Id
15668
Core Evidence Id
15668
Source Meta Analysis Id
7097
Herb2 Meta Analysis Id
HBMA007097
Crd Id
CRD42023413131
Title
Effect of dietary alpha-linolenic acid supplementation on inflammatory biomarkers in individuals with dyslipidemias: A systematic review and meta-analysis of randomized controlled trials
Review Question
This systematic review and meta-analysis aims to investigate the effects of supplementation with ALA on inflammatory biomarker in individuals with dyslipidemias.
Study Type Included
Randomized controlled trials with parallel or crossover design
Condition Being Studied
Dyslipidemias.
Participant
Adults with dyslipidemias, excluded if participants were pediatric and adolescent patients or pregnant women and nursing mothers and enteral or parenteral feeding.
Animal
Human Disease Modelled
Intervention
Dietary supplementation with ALA (including using flaxseed oil, chia seed oil, linseed oil, canola oil, rapeseed oil, walnut oil, perilla oil and their derivates as sources of ALA)
Comparator Control
Placebo or Control group
Main Outcome
Primary outcomes of interest will be inflammation biomarkers, including of C-reactive protein (CRP), hs-CRP, interleukin (IL)-6, and tumor necrosis factor (TNF)-α.
Outcome Measure
Additional Outcome
None.
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Biomarkers; Dietary Supplements; Dyslipidemias; Humans; Randomized Controlled Trials as Topic; alpha-Linolenic Acid
Contact
Shiyu Yin [email protected]
Organisational Affiliation
Southeast Univertisy
Funding Source
This work was funded by National Natural Science Foundation of China Grant number(s) State the funder, grant or award number and the date of award Grant No. 82173509
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-03-31
Registration Date
2023-04-10
Anticipated Start Date
2023-02-25
Anticipated Completion Date
2023-04-30
Title Cn
膳食补充α-亚麻酸对血脂异常患者炎性生物标志物影响的随机对照试验系统评价与Meta分析
Title En
Effect of dietary alpha-linolenic acid supplementation on inflammatory biomarkers in individuals with dyslipidemias: A systematic review and meta-analysis of randomized controlled trials
Bilingual Status
complete