Meta AnalysisID 7109
亚麻籽对健康人群血脂谱影响的临床试验系统评价与剂量反应Meta分析
CRD42023491817
Does flaxseed compared with placebo affect the lipid profile in healthy people?
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Record Fields
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- Meta Analysis Id
- 7109
- Evidence Id
- 15667
- Core Evidence Id
- 15667
- Source Meta Analysis Id
- 7096
- Herb2 Meta Analysis Id
- HBMA007096
- Crd Id
- CRD42023491817
- Title
- The effect of flaxseed on lipid profile in healthy individuals: a systematic review and dose-response meta-analysis of clinical trials
- Review Question
- Does flaxseed compared with placebo affect the lipid profile in healthy people?
- Study Type Included
- clinical trials
- Condition Being Studied
- Lipids are essential constituents of cellular membranes and they act as a storage material and signaling molecules in cellular response pathways. Although they are vital for cellular structure and function, abnormal levels results in the progression of atherosclerosis.
- Participant
- the studies will be included if they are human randomized controlled trials (RCT; either parallel or cross-over designs) reported flaxseed's influence on lipid profile The following studies were excluded: (a) did not utilize flaxseed alone; (b) were non-clinical; (c) did not give adequate information on flaxseed's effect on lipid profile before and after the trial; and (d) those that were not conducted on healthy persons.
- Animal
- Human Disease Modelled
- Intervention
- Flax (Linum usitatissimum) is a food and fiber crop. Flaxseeds are a good source of dietary fiber and omega-3 fatty acids, including alpha-linolenic acid. Flaxseeds also contain phytoestrogens called lignans, which are similar to the hormone estrogen. The fiber in flaxseed is found in the seed coat.
- Comparator Control
- placebo
- Main Outcome
- total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), Apolipoprotein -A (apo-A) and Apolipoprotein -B (apo-B) Measures of effect mean difference
- Outcome Measure
- Additional Outcome
- Study Method
- Intervention, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Zeinab Nikniaz [email protected]
- Organisational Affiliation
- Liver and gastrointestinal disease research center, Tabriz University of medical sciences, Tabriz_Iran
- Funding Source
- Semnan University of medical sciences, Iran
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-12-09
- Registration Date
- 2023-12-20
- Anticipated Start Date
- 2023-12-16
- Anticipated Completion Date
- 2024-01-31
- Title Cn
- 亚麻籽对健康人群血脂谱影响的临床试验系统评价与剂量反应Meta分析
- Title En
- The effect of flaxseed on lipid profile in healthy individuals: a systematic review and dose-response meta-analysis of clinical trials
- Bilingual Status
- complete