Meta AnalysisID 7106

柠檬香茅治疗口腔念珠菌病的有效性系统评价

CRD42023437844

Is lemon verbena effective against oral candidiasis in patients who have it? P: Patients with oral candidiasis I: Treatment with essential oil Lemon verbena (Cymbopogon citratus) C: Conventional pharmacological treatment

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Record Fields

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Meta Analysis Id
7106
Evidence Id
15664
Core Evidence Id
15664
Source Meta Analysis Id
7088
Herb2 Meta Analysis Id
HBMA007088
Crd Id
CRD42023437844
Title
Effectiveness of Lemon verbena (Cymbopogon citratus) in patients with oral candidiasis. Systematic Review.
Review Question
Is lemon verbena effective against oral candidiasis in patients who have it? P: Patients with oral candidiasis I: Treatment with essential oil Lemon verbena (Cymbopogon citratus) C: Conventional pharmacological treatments (fluconazole, nystatin) O: Effectiveness of the plant species (lemon verbena, Cymbopogon citratus), sensitivity and specificity.
Study Type Included
Clinical Trials.
Condition Being Studied
Oral candidiasis is a pathology that occurs in immunocompromised patients, in this case we will refer to the oral cavity causing gingivostomatitis drastically affecting the quality of life of patients who wear oral prostheses, causing pain, discomfort and difficulty for their usual feeding, This can be complicated if it is not treated immediately, there are conventional pharmacological treatments which have presented failures and its use reports hepatotoxicity in the individual, for this reason it is desired to make an exhaustive search of other therapeutic options such as phytotherapy in this case the lemon verbena against this pathology.
Participant
Reports of clinical studies reporting the efficacy of active components of lemon verbena against candida albicans versus conventional drug treatments will be studied. We will exclude literature reviews, letters to the editor, opinion articles, book chapters, congress abstracts; in vitro studies or animal model studies; qualitative research; observational studies; non-randomized or non-parallel clinical trials; and articles that do not have access to complete information.
Animal
Human Disease Modelled
Intervention
Reports of clinical studies reporting data on the efficacy of active components of Lemon verbena (Cymbopogon citratus) against commonly used pharmacological treatments with drugs such as: nystatin, fluconazole, ketoconazole, miconazole, itroconazole will be considered. Literature reviews, letters to the editor, opinion articles, book chapters, conference abstracts; in vitro or animal model studies; qualitative research; observational studies; non-randomized or non-parallel clinical trials; and articles that do not have access to complete information will be excluded.
Comparator Control
The comparandum will be pharmacological drug therapy used in gingivostomatitis such as nystatin, fluconazole, ketoconazole, miconazole, itroconazole.
Main Outcome
Antifungal effect of active components of lemon verbena in gingivostomatitis.
Outcome Measure
Additional Outcome
Study Method
Systematic review
Keyword
Aloysia; Candidiasis; Candidiasis, Oral; Citrus; Cymbopogon; Fluconazole; Humans; Nystatin; Oils, Volatile; Verbena
Contact
Katherine Cuenca-León [email protected]
Organisational Affiliation
Universidad Católica de Cuenca. Universidad de Salamanca.
Funding Source
Catholic University of Cuenca. Project: "DESIGN AND DEVELOPMENT OF A MOUTH RINSE WITH NATURAL ACTIVE INGREDIENTS INGREDIENTS, TO NEUTRALIZE AND ELIMINATE ORAL FUNGUS IN PATIENTS WEARING IN PATIENTS WITH PARTIAL AND/OR TOTAL PROSTHESIS" . Code: PICODS21- 21
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Ecuador
Review Stage
Review Ongoing
First Submission Date
2023-06-19
Registration Date
2023-06-30
Anticipated Start Date
2023-06-19
Anticipated Completion Date
2024-01-26
Title Cn
柠檬香茅治疗口腔念珠菌病的有效性系统评价
Title En
Effectiveness of Lemon verbena (Cymbopogon citratus) in patients with oral candidiasis. Systematic Review.
Bilingual Status
complete