Meta AnalysisID 7100

补充藏红花对代谢综合征组分的影响:系统评价与Meta分析

CRD42023462534

Does saffron supplement have an effect on improving the components of metabolic syndrome in patients with metabolic syndrome and related diseases?

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Record Fields

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Meta Analysis Id
7100
Evidence Id
15658
Core Evidence Id
15658
Source Meta Analysis Id
7080
Herb2 Meta Analysis Id
HBMA007080
Crd Id
CRD42023462534
Title
Effects of saffron supplementation on the components of metabolic syndrome: A Systematic Review and Meta-Analysis
Review Question
Does saffron supplement have an effect on improving the components of metabolic syndrome in patients with metabolic syndrome and related diseases?
Study Type Included
Only randomized controlled trials (RCTs) will be included.
Condition Being Studied
Metabolic syndrome encompasses a range of metabolic disorders within the body, involving irregularities in glucose and lipid metabolism, central obesity, and hypertension. This syndrome has been gradually recognized as a significant contributor to the development of cardiovascular and cerebrovascular diseases, proving to be a substantial risk factor for these conditions.
Participant
The population of interest was patients with metabolic syndrome or with disorders of glucose, lipid, and blood pressure metabolism (age≥18 years).
Animal
Human Disease Modelled
Intervention
saffron or crocin
Comparator Control
control: placebo
Main Outcome
Main outcomes include triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), fasting blood glucose (FBG), and blood pressure (SBP, DBP). Measures of effect The outcome indicators selected for this study are all continuous variables, which will be analyzed through the application of weighted mean difference (WMD).
Outcome Measure
Additional Outcome
Additional outcomes include abdominal circumference (WC) and body mass index (BMI). Measures of effect The outcome indicators selected for this study are all continuous variables, which will be analyzed through the application of weighted mean difference (WMD).
Study Method
Systematic review
Keyword
Biological Products; Coloring Agents; Crocus; Dietary Supplements; Humans; Metabolic Syndrome
Contact
xiaolei zhang [email protected]
Organisational Affiliation
Henan University of Chinese Medicine
Funding Source
National Major Scientific and Technological Special Project for “Significant New Drugs Development”, Grant/Award Number: 2017ZX09301071; Henan Province Major Public Welfare Special Projects, Grant/Award: 201300310100; Henan Province Scientific and Technological Research Projects, Grant/Award: 212102310351
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-09-11
Registration Date
2023-09-21
Anticipated Start Date
2023-09-15
Anticipated Completion Date
2023-11-15
Title Cn
补充藏红花对代谢综合征组分的影响:系统评价与Meta分析
Title En
Effects of saffron supplementation on the components of metabolic syndrome: A Systematic Review and Meta-Analysis
Bilingual Status
complete