Meta AnalysisID 7094
西番莲果皮和果肉作为代谢综合征组分的替代疗法：随机临床试验的系统评价
CRD42023488150
Solid residues (peel and pulp) of Passiflora ssp. attenuate the components of metabolic syndrome? PICOS: ( "passion fruit" OR "passionflower" OR "passion flower" OR "passiflora" OR "passifloraceae" ) AND ( "mesocarp" OR
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Record Fields
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- Meta Analysis Id
- 7094
- Evidence Id
- 15652
- Core Evidence Id
- 15652
- Source Meta Analysis Id
- 7074
- Herb2 Meta Analysis Id
- HBMA007074
- Crd Id
- CRD42023488150
- Title
- Passiflora ssp. peel and pulp as alternative therapy in the components of metabolic syndrome: A systematic review of randomized clinical trials
- Review Question
- Solid residues (peel and pulp) of Passiflora ssp. attenuate the components of metabolic syndrome? PICOS: ( "passion fruit" OR "passionflower" OR "passion flower" OR "passiflora" OR "passifloraceae" ) AND ( "mesocarp" OR "bark" OR "rind" OR "peel" OR "seed" OR "leaf" OR "stalk" OR "pulp" OR "residue" OR "flour" OR "extract" OR "powder" OR "oils" ) AND ( "insulin resistance" OR "glucose metabolism disorders" OR "hyperinsulinism" OR "diabetes mellitus" OR "glucose intolerance" OR "fasting blood glucose" OR "hyperglycemia" OR "overweight" OR "obesity" OR "waist-hip ratio" OR "body fat distribution" OR "waist circumference" OR "body mass index" OR "hypertension" OR "high blood pressure" OR "systolic pressure" OR "diastolic pressure" OR "dyslipidemia" OR "hyperlipidemia" OR "hypercholesterolemia" OR "hypertriglyceridemia" OR "triglycerides" OR "metabolic syndrome" )
- Study Type Included
- randomized clinical trials
- Condition Being Studied
- Metabolic Syndrome (MS) has been characterized by a set of cardiometabolic disorders, which encompasses physiological, biochemical, clinical and metabolic changes directly related to heredity and lifestyle. The diagnosis of MS includes the presence of some components, namely: insulin resistance (IR), atherogenic dyslipidemia, central obesity and systemic arterial hypertension (SAH). It is worth noting that there is no specific treatment for MS, but its therapy mainly aims to mitigate and prevent the risk of major complications, through behavioral strategies (lifestyle and eating habits) associated or not with the use of pharmacological medications. Studies have shown that diets rich in fresh foods, such as the DASH (Dietary Approach to Stop Hypertension) and Mediterranean diets, improve the lipidemic profile, blood glucose, blood pressure levels and oxidative stress, providing health benefits. In view of these discoveries, scholars have focused on the study of natural products, with an emphasis on the full use of these products, in order to encourage environmental sustainability, as well as their potential biological effects on human health. The genus Passiflora ssp. stands out for its diversity, highlighted by its therapeutic properties, due to its bioactive compounds.
- Participant
- in adult individuals, regardless of age and anthropometric classification, country, ethnicity and socioeconomic level who had components of metabolic syndrome
- Animal
- Human Disease Modelled
- Intervention
- Intervention: solid waste (peel, pulp, leaves or seeds) of passionflower ssp. in any presentation, be it flour, capsule, tablet, drinks in general, among others.
- Comparator Control
- placebo
- Main Outcome
- It is intended to identify that the use of solid waste from Passiflora ssp. is safe for adult individuals and can attenuate inflammation, glucose, insulin, dyslipidemic and blood pressure parameters, so that it can be concluded that its use be considered as an alternative therapy for metabolic syndrome. Measures of effect odds ratios or treat
- Outcome Measure
- Additional Outcome
- not applicable Measures of effect odds ratios or treat
- Study Method
- Intervention, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Isabelle Gama [email protected]
- Organisational Affiliation
- Universidade Federal de Alagoas
- Funding Source
- Isabelle Gama, undergraduate nutrition student at the Federal University of Alagoas. Elaine Mendonça, nutritionist, specialist in phytotherapy applied to clinical nutrition, master in human nutrition and doctoral student in health biotechnology. Alane Oliveira, nutritionist, PhD in health biotechnology and master in health sciences. Associate professor at the Federal University of Alagoas studying areas of pathophysiology of human diseases and experimental therapeutics. Grant number(s) State the funder, grant or award number and the date of award not applicable
- Other Selection Criteria
- Final Publication
- Same Topic Review
- not applicable
- Published Protocol
- Review Type
- Language
- English
- Country
- Brazil
- Review Stage
- Review Completed not published
- First Submission Date
- 2023-11-29
- Registration Date
- 2023-12-12
- Anticipated Start Date
- 2023-01-08
- Anticipated Completion Date
- 2024-02-01
- Title Cn
- 西番莲果皮和果肉作为代谢综合征组分的替代疗法：随机临床试验的系统评价
- Title En
- Passiflora ssp. peel and pulp as alternative therapy in the components of metabolic syndrome: A systematic review of randomized clinical trials
- Bilingual Status
- complete