Meta AnalysisID 7088
石榴对代谢相关脂肪性肝病患者影响的系统评价与Meta分析
CRD42023491983
How does the consumption of pomegranate impact the health of individuals diagnosed with metabolic associated liver disease?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7088
- Evidence Id
- 15646
- Core Evidence Id
- 15646
- Source Meta Analysis Id
- 7067
- Herb2 Meta Analysis Id
- HBMA007067
- Crd Id
- CRD42023491983
- Title
- Systematic review and meta-analysis of the impact of pomegranate in individuals diagnosed with metabolic associated fatty liver disease
- Review Question
- How does the consumption of pomegranate impact the health of individuals diagnosed with metabolic associated liver disease?
- Study Type Included
- Inclusion: Randomized controlled trials Exclusion: Non-RCTs or studies with an inappropriate design (e.g., observational studies, case reports, reviews). Non-peer-reviewed studies or those lacking full-text availability. Studies published in languages not specified for inclusion.
- Condition Being Studied
- Metabolic associated fatty liver disease/nonalcoholic fatty liver disease
- Participant
- Inclusion: individuals diagnosed with Metabolic Associated Fatty Liver Disease (MAFLD), Nonalcoholic Fatty Liver Disease (NAFLD), or Nonalcoholic Steatohepatitis (NASH). Exclusion: Individuals without a confirmed diagnosis of MAFLD/NAFLD or NASH. Studies involving populations with other liver diseases (e.g., viral hepatitis, alcoholic liver disease).
- Animal
- Human Disease Modelled
- Intervention
- Inclusion: consumption of pomegranate or pomegranate derived products, such as juice, extract, or supplement Exclusion: studies investigating interventions other than pomegranate or its derivatives.
- Comparator Control
- Inclusion: Placebo. No treatment. Alternative interventions unrelated to pomegranate consumption. Exclusion: Studies without a comparison group or using comparators related to pomegranate consumption.
- Main Outcome
- Inclusion: Liver function (AST and ALT levels); Diastolic and systolic pressures; Lipid panel (cholesterol and triglycerides); Anthropometric measures (BMI and wait circumference); Insulin resistance measures (HOMA-IR, fasting insulin); Liver stiffness (assessed via non-invasive methods such as transient elastography) Exclusion: Studies lacking measurement of any of the specified outcomes. Non-randomized studies or studies with inadequate randomization procedures. Measures of effect Mean Difference (MD)
- Outcome Measure
- Additional Outcome
- Not applicable
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Islam Mohamed [email protected]
- Organisational Affiliation
- University of Missouri Kansas City https://med.umkc.edu/
- Funding Source
- Not applicable
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- United States of America
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-12-10
- Registration Date
- 2023-12-20
- Anticipated Start Date
- 2023-12-09
- Anticipated Completion Date
- 2024-01-07
- Title Cn
- 石榴对代谢相关脂肪性肝病患者影响的系统评价与Meta分析
- Title En
- Systematic review and meta-analysis of the impact of pomegranate in individuals diagnosed with metabolic associated fatty liver disease
- Bilingual Status
- complete