Meta AnalysisID 7016
口服芦荟补充剂对皮肤皱纹、水合作用、弹性、经皮水分丢失和胶原蛋白评分的疗效：随机对照试验的系统评价与Meta分析
CRD42023412335
Does aloe vera oral supplementation has any effect on skin wrinkles, hydration, elasticity, TEWL, or collagen score?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7016
- Evidence Id
- 15574
- Core Evidence Id
- 15574
- Source Meta Analysis Id
- 7001
- Herb2 Meta Analysis Id
- HBMA007001
- Crd Id
- CRD42023412335
- Title
- Efficacy of Oral Aloe Vera Supplementation on Skin wrinkles, Hydration, Elasticity, Transepidermal Water Loss and Collagen Score: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review Question
- Does aloe vera oral supplementation has any effect on skin wrinkles, hydration, elasticity, TEWL, or collagen score?
- Study Type Included
- only RTCs
- Condition Being Studied
- Wrinkles are major features of aging; and skin hydration, skin elasticity, transepidermal water loss (TEWL), and collagen score are some parameters used in measuring the skin’s resilience to wrinkles. Orally administered aloe vera supplements have shown promise in alleviating some of these skin aging parameters. To determine the effects of oral aloe vera supplements on skin wrinkles, hydration, elasticity, TEWL, and collagen score compared with placebo or no treatment.
- Participant
- Healthy adults between 18 to 80.
- Animal
- Human Disease Modelled
- Intervention
- Oral preparations of Aloe Vera supplementation.
- Comparator Control
- Placebo and no treatment in randomized controlled trials (RCTs)
- Main Outcome
- Wrinkle mean depth, maximum width, skin hydration, TEWL, collagen score, and skin elasticity will be assessed as outcomes. Measures of effect since the outcomes are continuous, mean difference or standardized mean difference will be assessed.
- Outcome Measure
- Additional Outcome
- • Changes in skin image as measured by Visiometer or photograph • Wrinkles mean depth, intensity, and distribution measured by skin replica. Measures of effect Since the outcomes are continuous, mean difference or standardized mean difference will be assessed.
- Study Method
- Intervention, Systematic review
- Keyword
- Humans
- Contact
- Fatemeh Mirzayeh Fashami [email protected]
- Organisational Affiliation
- McMaster University
- Funding Source
- No funding was received for this study. Grant number(s) State the funder, grant or award number and the date of award NA
- Other Selection Criteria
- Final Publication
- Same Topic Review
- No similar reviews are available.
- Published Protocol
- Review Type
- Language
- English
- Country
- Canada
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-03-28
- Registration Date
- 2023-04-08
- Anticipated Start Date
- 2023-03-28
- Anticipated Completion Date
- 2023-04-26
- Title Cn
- 口服芦荟补充剂对皮肤皱纹、水合作用、弹性、经皮水分丢失和胶原蛋白评分的疗效：随机对照试验的系统评价与Meta分析
- Title En
- Efficacy of Oral Aloe Vera Supplementation on Skin wrinkles, Hydration, Elasticity, Transepidermal Water Loss and Collagen Score: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Bilingual Status
- complete