Meta AnalysisID 7000
甘草提取物对口腔健康的影响：系统评价与Meta分析
CRD42023476073
Does Liquorice have the potential to influence the activities in oral cavity , thus bringing down the level of dental caries, gingivitis, oral ulcers and mucositis?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Herb: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 7000
- Evidence Id
- 15558
- Core Evidence Id
- 15558
- Source Meta Analysis Id
- 6985
- Herb2 Meta Analysis Id
- HBMA006985
- Crd Id
- CRD42023476073
- Title
- Effect of liquorice extract on oral health - A systematic review and meta analysis
- Review Question
- Does Liquorice have the potential to influence the activities in oral cavity , thus bringing down the level of dental caries, gingivitis, oral ulcers and mucositis?
- Study Type Included
- All published articles of Clinical trials and in-vivo studies investigating the effect of liquorice extract on both men and women between the age of 3-55 years with the history of high dental caries, initial enamel lesion, moderate gingivitis, children receiving orthodontic treatment and ulcers are included for this study. All english articles published between the year 2017-2023 are taken into consideration.
- Condition Being Studied
- effect of liquorice extract on dental caries, gingivitis, plaque, mucositis and oral ulcers.
- Participant
- Population – Patients of age 3-55 years with high caries risk, undergoing removable orthodontic treatment, patients with minimal enamel caries with 16 or more teeth in dentition, and with moderate gingivitis were included in this analysis and patients with recurrent aphthous stomatitis and head & neck cancer were included in this analysis.
- Animal
- Human Disease Modelled
- Intervention
- Intervention – 1% , 2% and 16% of liquorice mouthwash, liquorice lozenges, lollipops containing liquorice extracts, liquorice containing diphenhydramine solution were intervened separately to analyse the outcome on oral health status and disease condition.
- Comparator Control
- Comparison – 0.2% of chlrohexidine mouthwash, saline and control group receiving counselling on maintaining oral health were taken as comparison groups to assess the intervention
- Main Outcome
- Outcome – Active reduction in streptococcus mutans level which is the key organism responsible for dental caries, significant remineralisation property and reduction of gingival and plaque index were noted after the oral cavity has been exposed to the various forms of liquorice extract. Liquorice also increased the rate of wound healing and lessens the mucosal irritation. Measures of effect relative risk, odds ratio
- Outcome Measure
- Additional Outcome
- nil Measures of effect relative risk, odds ratio
- Study Method
- Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Kiruppashini Thiagarajan [email protected]
- Organisational Affiliation
- Karpaga vinayaga institute of dental sciences [email protected]
- Funding Source
- nil Grant number(s) State the funder, grant or award number and the date of award nil
- Other Selection Criteria
- Final Publication
- Same Topic Review
- nil
- Published Protocol
- Review Type
- Language
- English
- Country
- India
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-12-02
- Registration Date
- 2023-12-13
- Anticipated Start Date
- 2023-09-25
- Anticipated Completion Date
- 2024-02-20
- Title Cn
- 甘草提取物对口腔健康的影响：系统评价与Meta分析
- Title En
- Effect of liquorice extract on oral health - A systematic review and meta analysis
- Bilingual Status
- complete