Meta AnalysisID 6999
甘草（Glycyrrhiza glabra）对比其他药物干预（包括安慰剂）在减轻复发性阿弗他口炎、口腔扁平苔藓和放射性口腔黏膜炎患者疼痛中的疗效
CRD42023466926
Does licorice(Glycyrrhiza glabra) has pain reducing effect on recurrent aphhous stomatitis, oral lichen planus and radiation induced oral mucositis patients as compare to other pharmacological interventions including pla
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 6999
- Evidence Id
- 15557
- Core Evidence Id
- 15557
- Source Meta Analysis Id
- 6984
- Herb2 Meta Analysis Id
- HBMA006984
- Crd Id
- CRD42023466926
- Title
- Efficacy of licorice(Glycyrrhiza glabra) in reducing pain as compare to other pharmacological interventions including placebo in recurrent aphthous stomatitis, oral lichen planus, and radiation induced oral mucositis patients.
- Review Question
- Does licorice(Glycyrrhiza glabra) has pain reducing effect on recurrent aphhous stomatitis, oral lichen planus and radiation induced oral mucositis patients as compare to other pharmacological interventions including placebo ?
- Study Type Included
- RCT
- Condition Being Studied
- Discomfort and pain are classic prodromal symptoms that arise 24-48 hours before the onset of the ulcer. A typical aphthous ulcer is a painful round or oval lesion measuring 1- 5 mm in diameter . It is an inflammatory illness whose cause is unclear. It has been stated that it affects 5-25% of the normal population, however depending on the group examined, it may impact 50% of the population. Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory disease that causes skin and oral mucous membrane eruptions. The disease's etiology is unknown; however it has been linked to stress and viral infections. Atrophic and erosive versions of this illness are often painful. Radiation-induced oral mucositis is related with radiation treatment as a direct consequence and as a secondary effect due to increased effects of physical, chemical, and microbiological insults in the mouth. Mucosal breakdown is painful and can interfere with oral functions. It can cause considerable discomfort, dysphagia, a change in nutritional status, and an increased risk of localized infections that can spread systemically
- Participant
- Patients with recurrent aphthous ulcer, oral lichen planus, radiation induced oral mucositis
- Animal
- Human Disease Modelled
- Intervention
- Licorice(Glycyrrhiza glabra) in any formulation.
- Comparator Control
- Other pharmacological interventions including placebo.
- Main Outcome
- Reduction in pain intensity Measures of effect VAS: visual analogue scale
- Outcome Measure
- Additional Outcome
- Ulcer size
- Study Method
- Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Dr Disha Vijay Alhat [email protected]
- Organisational Affiliation
- Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur
- Funding Source
- Self
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- India
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-09-25
- Registration Date
- 2023-10-06
- Anticipated Start Date
- 2024-01-05
- Anticipated Completion Date
- 2024-05-25
- Title Cn
- 甘草（Glycyrrhiza glabra）对比其他药物干预（包括安慰剂）在减轻复发性阿弗他口炎、口腔扁平苔藓和放射性口腔黏膜炎患者疼痛中的疗效
- Title En
- Efficacy of licorice(Glycyrrhiza glabra) in reducing pain as compare to other pharmacological interventions including placebo in recurrent aphthous stomatitis, oral lichen planus, and radiation induced oral mucositis patients.
- Bilingual Status
- complete