Meta AnalysisID 6973

草药补充剂对肝酶水平的影响:系统评价与Meta分析

CRD42023481625

In individuals using herbal and dietary supplements, what is the impact of these supplements on liver enzyme levels (ALT, AST, ALP) compared to those not using supplementation or receiving a placebo/control, assessed ove

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Record Fields

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Meta Analysis Id
6973
Evidence Id
15531
Core Evidence Id
15531
Source Meta Analysis Id
6954
Herb2 Meta Analysis Id
HBMA006954
Crd Id
CRD42023481625
Title
Impact of Herbal Supplements on Liver Enzyme Levels: A Systematic Review and Meta-analysis
Review Question
In individuals using herbal and dietary supplements, what is the impact of these supplements on liver enzyme levels (ALT, AST, ALP) compared to those not using supplementation or receiving a placebo/control, assessed over a longitudinal period?
Study Type Included
This review has strict inclusion criteria regarding study design and will include only randomized or semi-randomized controlled trials published from 1992 to 2023. We excluded letters to the editor, reviews, systematic reviews, meta analysis, case control, cross sectional, retrospective or prospective cohorts, and single arm studies
Condition Being Studied
Hepatic disease, Gastroenterology, treatment, Prevention
Participant
Adult Individuals (>65 years) using herbal and dietary supplements
Animal
Human Disease Modelled
Intervention
Consumption of herbal and dietary supplements such as such as licorice root, garlic, green tea, Artichoke Leaf Extract, dandelion, ginger, Curcumin, sylimarin
Comparator Control
No supplementation, standard treatment or placebo/control group.
Main Outcome
Only studies reporting our outcomes of interest, that is, levels of liver enzymes, including Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), and Alkaline Phosphatase (ALP) will be included. Studies that did not report these outcomes will not be considered for inclusion. Measures of effect Number needed to treat to avoid complications
Outcome Measure
Additional Outcome
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
MeSH headings have not been applied to this record
Contact
Ernesto Calderon Martinez [email protected]
Organisational Affiliation
Universidad Nacional Autonoma de Mexico
Funding Source
No funding sources
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Mexico
Review Stage
Review Ongoing
First Submission Date
2023-11-10
Registration Date
2023-11-20
Anticipated Start Date
2023-10-01
Anticipated Completion Date
2024-01-09
Title Cn
草药补充剂对肝酶水平的影响:系统评价与Meta分析
Title En
Impact of Herbal Supplements on Liver Enzyme Levels: A Systematic Review and Meta-analysis
Bilingual Status
complete