Meta AnalysisID 6963
草药对非感染性人体皮肤伤口愈合过程的影响
CRD42023424727
Does the implication of herbal medicines affect the healing process of non-infected human skin wounds?
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Record Fields
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- Meta Analysis Id
- 6963
- Evidence Id
- 15521
- Core Evidence Id
- 15521
- Source Meta Analysis Id
- 6943
- Herb2 Meta Analysis Id
- HBMA006943
- Crd Id
- CRD42023424727
- Title
- Effect of herbal medicine in the healing process of non-infected human skin wounds
- Review Question
- Does the implication of herbal medicines affect the healing process of non-infected human skin wounds?
- Study Type Included
- Randomized controlled study Non-randomized controlled study Exclusion criteria: Reviews Meta-analysis Studies without an experiment Supplements from conferences Case studies Case-control Cohort study
- Condition Being Studied
- Herbal medicine interventions for wound healing, investigate the effect and efficacy of medicinal plants on the healing process (recovery time, infection prevention, erythema and redness reduction, pain and itchiness alleviation, discharge and bleeding depletion, and moisture retention) of dermatic non-infectious injuries due to numerous causative factors.
- Participant
- Inclusion criteria: Adults with various forms of skin ulcers and wounds due to: pressure (decubitus ulcer), diabetes, burns (chemical, electric, sunburn), trauma, surgery (incision), bites and stings Exclusion criteria: Visceral ulcers, Infectious ulcers (demanding antibiotic therapy), Venous hypertension (venous stasis- varicose).
- Animal
- Human Disease Modelled
- Intervention
- Any studies of herbal medicine or herbal extracts. Examples of pharmaceutical herbs include: rosemary, pistacia Lentiscus, purslane, curcuma longa, arnebia euchroma, flaxseed oil, lavender, malva sylvestris, symphytum, aloe vera, myrrh, centella asiatica, calendula officinalis, soybean, silybum marianum, Tannin, onion (Allium cepa, Linn), Garlic (Allium sativum, Linn.), chamomile, green tea, olea europaea, verbascum thapsus, achillea millefalium, tangzu yuyang, St. John’s Wort (Hypericum Perforatum), arreca catechu, hibiscus rosa sinensis, panax notoginseng and neem ( azadirachta indica).
- Comparator Control
- Placebo - no treatment - synthetic medicines - dressing
- Main Outcome
- 1. Healing time 2. Changes in the wound size 3. Pain Measures of effect 1. To measure the duration of wound healing, we will consider the number of days it takes for the wound to heal completely. 2. The wound size is typically measured first by its length, then by width, and finally by depth. 3. To measure the intensity of pain, the VAS scale will be used, which is graded from zero to ten, where ten means unbearable pain and zero means no pain.
- Outcome Measure
- Additional Outcome
- 1- Itching 2- Discharge and/or bleeding 3- Patient satisfaction 4- Redness 5- Infection Measures of effect 1-On the NRS, patients will score itch intensity on a scale of 0 (no itch) to 10 (worst imaginable itch) over a period of time, typically 24 hours. 2- Small or minimal amount of discharge/bleeding on the wound's dressing refers to wounds whose exudate covers less than 25% of the bandage. Moderate-amount wound tissues are wet, and exudation involves 25% to 75% of the bandage. Large or copious–amount wounds are filled with fluid, and exudate covers more than 75% of the bandage. 3-Patient satisfaction will be evaluated via questionnaires investigating the impact of wounds on quality of life aspects: psychological characteristics, social life, and sleep for instance. 4- Presence of visually observable redness 5- Presence of active infection
- Study Method
- Intervention, Systematic review
- Keyword
- Herbal Medicine; Humans; Plants, Medicinal; Skin; Wound Healing
- Contact
- Mohammad Hosein Amirzade-Iranaq [email protected]
- Organisational Affiliation
- Universal Network of Interdisciplinary Research in Oral and Maxillofacial Surgery (UNIROMS), Universal Scientific Education and Research Network (USERN), Tehran, Iran. https://usern.tums.ac.ir/Group/Info/UNIROMS
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-05-08
- Registration Date
- 2023-05-19
- Anticipated Start Date
- 2023-01-01
- Anticipated Completion Date
- 2023-07-01
- Title Cn
- 草药对非感染性人体皮肤伤口愈合过程的影响
- Title En
- Effect of herbal medicine in the healing process of non-infected human skin wounds
- Bilingual Status
- complete