Meta AnalysisID 6935
刺毛黧豆对男性不育的影响：一项系统评价和Meta分析
CRD42023425641
What are the beneficial and adverse effects of Velvet Bean (Mucuna pruriens) in the management of male infertility?
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Record Fields
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- Meta Analysis Id
- 6935
- Evidence Id
- 15493
- Core Evidence Id
- 15493
- Source Meta Analysis Id
- 6920
- Herb2 Meta Analysis Id
- HBMA006920
- Crd Id
- CRD42023425641
- Title
- Effect of Mucuna pruriens on male infertility: A systematic review and meta-analysis
- Review Question
- What are the beneficial and adverse effects of Velvet Bean (Mucuna pruriens) in the management of male infertility?
- Study Type Included
- We will include following type of study designs: Randomized Control Trials Experimental Study Observational study
- Condition Being Studied
- Male infertility is a medical condition that affects a significant proportion of couples trying to conceive. It is characterized by the inability of a man to contribute to conception despite frequent unprotected sexual intercourse with their partner. Semen analysis is a critical diagnostic tool for assessing male fertility potential, which includes the evaluation of various semen parameters such as sperm count, motility, morphology, and volume. Understanding the causes and factors that contribute to male infertility and semen parameter abnormalities is crucial for effective diagnosis, treatment, and management of this condition.
- Participant
- The participants or populations of this systematic review is both human (male individuals with infertility) as well as the animal model. The study likely includes participants from various backgrounds and demographics who have been diagnosed with male infertility or have reported abnormal semen parameters during fertility evaluations. The review aims to assess the effectiveness of velvet bean (Mucuna pruriens) as a potential treatment or intervention for male infertility and semen parameter abnormalities in this population.
- Animal
- Human Disease Modelled
- Intervention
- Mucuna pruriens (seed extract or whole) is the intervention for this review.
- Comparator Control
- The control or comparator for this systematic review is infertile human males or animal (mice) kept in the laboratory in the controlled environment treated with placebo or treated with different other treatments or controls who did not receive any treatment.
- Main Outcome
- The main outcomes are improvement in semen parameters sperm count, volume, motility, morphology, and concentration, hormonal level, successful conception, and adverse events related to the intervention of Mucuna pruriens.
- Outcome Measure
- Additional Outcome
- Other potential health benefits and harm of Mucuna pruriens.will be the additional outcome
- Study Method
- Intervention, Meta-analysis, Narrative synthesis, Pre-clinical, Systematic review
- Keyword
- Drug-Related Side Effects and Adverse Reactions; Humans; Iatrogenic Disease; Infertility, Male; Male; Mucuna
- Contact
- Kapil Amgain [email protected]
- Organisational Affiliation
- Karnali Academy of Health Sciences, Jumla, Nepal https://kahs.edu.np/
- Funding Source
- No external funding received to conduct this systematic review.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Nepal
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-05-17
- Registration Date
- 2023-05-27
- Anticipated Start Date
- 2023-06-01
- Anticipated Completion Date
- 2024-07-31
- Title Cn
- 刺毛黧豆对男性不育的影响：一项系统评价和Meta分析
- Title En
- Effect of Mucuna pruriens on male infertility: A systematic review and meta-analysis
- Bilingual Status
- complete