Meta AnalysisID 6932

角豆(Ceratonia siliqua)对不育男性精子特征的影响:一项系统评价和Meta分析

CRD42023420489

1: Is carob supplement effective in the treatment of male infertility? 2: Does carob improve reproductive parameters in infertile men? 3: Does carob have an effect on sperm parameters in infertile men?

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Record Fields

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Meta Analysis Id
6932
Evidence Id
15490
Core Evidence Id
15490
Source Meta Analysis Id
6917
Herb2 Meta Analysis Id
HBMA006917
Crd Id
CRD42023420489
Title
Effect of carob (Ceratonia siliqua) on sperm characteristics of infertile men: A systematic review and meta-analysis
Review Question
1: Is carob supplement effective in the treatment of male infertility? 2: Does carob improve reproductive parameters in infertile men? 3: Does carob have an effect on sperm parameters in infertile men?
Study Type Included
Randomized Controlled Trials
Condition Being Studied
Infertile men aged 20-65 years who use carob to improve sperm parameters and testicular function (regardless of duration of treatment).
Participant
Infertile men aged 20-65 years who use carob to improve sperm parameters and testicular function (regardless of duration of treatment).
Animal
Human Disease Modelled
Intervention
Carob (Ceratonia siliqua) supplement. Studies that use a standard diet throughout the treatment period will be selected. ​
Comparator Control
Infertile men who do not take carob supplements or a non-exposed control group
Main Outcome
Primary outcomes: Primary outcomes (1) Response rate to treatment as measured by spermatograms and hormonal assessments; (2) Changes in total sperm count, concentration, and motility as measured by spermatograms; (3) Testicular function as assessed by measuring testosterone, estradiol, FSH, and LH levels.
Outcome Measure
Additional Outcome
Secondary outcomes: (1) Effects of carob pretreatment in reducing sperm abnormalities assessed by spermatograms; (2) Incidence of treatment-emergent adverse events.
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
MeSH headings have not been applied to this record
Contact
Aysu YILDIZ KARAAHMET [email protected]
Organisational Affiliation
Halic Universty
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Turkey
Review Stage
Review Ongoing
First Submission Date
2023-12-08
Registration Date
2023-12-19
Anticipated Start Date
2023-12-08
Anticipated Completion Date
2024-02-08
Title Cn
角豆(Ceratonia siliqua)对不育男性精子特征的影响:一项系统评价和Meta分析
Title En
Effect of carob (Ceratonia siliqua) on sperm characteristics of infertile men: A systematic review and meta-analysis
Bilingual Status
complete