Meta AnalysisID 6929
菜蓟（Cynara scolymus L.）对心血管代谢结局的影响：随机对照试验的更新Meta分析和Meta回归
CRD42023421339
To determine the efficacy and safety of Cynara scolymus on blood glucose, lipid level, blood pressure and anthropometric parameters outcomes.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 6929
- Evidence Id
- 15487
- Core Evidence Id
- 15487
- Source Meta Analysis Id
- 6914
- Herb2 Meta Analysis Id
- HBMA006914
- Crd Id
- CRD42023421339
- Title
- Effect of Cynara scolymus L. on cardiometabolic outcomes: An update meta-analysis of randomizedcontrolled trials and meta-regression
- Review Question
- To determine the efficacy and safety of Cynara scolymus on blood glucose, lipid level, blood pressure and anthropometric parameters outcomes.
- Study Type Included
- Inclusion criteria: randomized controlled trials (RCTs) that demonstrated the effectiveness of artichoke for any outcome, including lipid profile, blood glucose, blood pressure, and anthropological parameters. Exclusion criteria: pre-post study, and non-RCT observational or cross-sectional study.
- Condition Being Studied
- 1. Blood glucose outcomes including fasting plasma glucose (FPG), HbA1C and Homeostasis model assessment of insulin resistance (HOMA-IR) of participants who use Cynara scolymus products. 2. Lipid profiles outcomes including LDL, HDL, triglyceride (TG), total cholesterol (TC) of participants who use Cynara scolymus products. 3. Blood pressure including systolic blood pressure (SBP) and diastolic blood pressure (DBP) of participants who use Cynara scolymus products. 4. Anthropometric parameters including body weight and body mass index (BMI) 5. Adverse events of participants who use Cynara scolymus products.
- Participant
- Inclusion criteria: all participants who use Cynara scolymus products including blood glucose, lipid profile, blood pressure and other conditions including body weight and body mass index reduction
- Animal
- Human Disease Modelled
- Intervention
- Inclusion criteria: the use of Cynara scolymus products in oral forms. Exclusion criteria: none.
- Comparator Control
- Inclusion criteria: any comparator or control product incorporates in control or non-intervention group. Exclusion criteria: none.
- Main Outcome
- Mean and standard deviations laboratory test of blood glucose, lipid profile, blood pressure and anthropometric parameters of participants after use Cynara scolymus products. Measures of effect Standardized mean difference (SMD) and 95% confident interval
- Outcome Measure
- Additional Outcome
- Any adverse effect reported in included trials. Measures of effect Relative risk (RR) and 95% confident interval
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Anthropometry; Cardiovascular Diseases; Cynara scolymus; Glucose; Humans; Lipids
- Contact
- Wiraphol Phimarn [email protected]
- Organisational Affiliation
- Mahasarakham University https://pharmacy.msu.ac.th/
- Funding Source
- Mahasarakham University Grant number(s) State the funder, grant or award number and the date of award 2566
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Thailand
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-04-25
- Registration Date
- 2023-05-06
- Anticipated Start Date
- 2023-04-25
- Anticipated Completion Date
- 2023-07-31
- Title Cn
- 菜蓟（Cynara scolymus L.）对心血管代谢结局的影响：随机对照试验的更新Meta分析和Meta回归
- Title En
- Effect of Cynara scolymus L. on cardiometabolic outcomes: An update meta-analysis of randomizedcontrolled trials and meta-regression
- Bilingual Status
- complete