Meta AnalysisID 6879
小檗碱补充剂对成人血压的影响：一项GRADE评估的随机安慰剂对照试验的系统评价和Meta分析
CRD42023455578
What is the impact of berberine supplementation on systolic blood pressure? What is the impact of berberine supplementation on diastolic blood pressure?
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Record Fields
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- Meta Analysis Id
- 6879
- Evidence Id
- 15437
- Core Evidence Id
- 15437
- Source Meta Analysis Id
- 6866
- Herb2 Meta Analysis Id
- HBMA006866
- Crd Id
- CRD42023455578
- Title
- The effect of berberine supplementation on blood pressure in adults: a GRADE-assessed systematic review and meta-analysis of randomized controlled-placebo trial studies
- Review Question
- What is the impact of berberine supplementation on systolic blood pressure? What is the impact of berberine supplementation on diastolic blood pressure?
- Study Type Included
- Randomized control trial studies whose control group received placebo.
- Condition Being Studied
- Hypertension, defined as having a systolic blood pressure (SBP) above 140 mm Hg and/or a diastolic blood pressure (DBP) above 90 mm Hg, is a major contributor to morbidity and mortality. It serves as a risk factor for various non-communicable diseases (NCDs) and cardiovascular diseases (CVDs). The prevalence of hypertension in developed nations is steadily rising, placing a significant strain on healthcare systems.
- Participant
- Studies were included based on our eligibility criteria: 1) studies should include adult participants (≥ 18 years old) who have been intake with a berberine for any reason, 2) studies should use any form of berberine 3) studies should design parallel and/or crossover RCTs that measure the blood pressure written in English, 4) studies should report the comparisons between an intervention and a control group, 5) articles were written in English. Studies were excluded as follows: 1) preclinical studie , 2) combination therapy with berberine, 3) no trial, animal studies, review articles, conference abstracts, and letters to editor articles, did not measure the blood pressure. 4)No use of placebo in the control group
- Animal
- Human Disease Modelled
- Intervention
- berberine consumption will be defined as follows: All forms include: Copti chinensi, Berberis aristata, Hydrastis canadensis, Berberis vulgaris.
- Comparator Control
- The control group received a placebo.
- Main Outcome
- blood pressure (systolic blood pressure and dyastolic blood pressure).
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Adult; Berberine; Blood Pressure; Dietary Supplements; Humans; Hypertension; Randomized Controlled Trials as Topic; Vital Signs
- Contact
- mostafa shahraki jazinaki [email protected]
- Organisational Affiliation
- Mashhad University of Medical Sciences
- Funding Source
- This systematic review will not receive any financial support Grant number(s) State the funder, grant or award number and the date of award None
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-08-18
- Registration Date
- 2023-08-28
- Anticipated Start Date
- 2023-03-27
- Anticipated Completion Date
- 2024-02-12
- Title Cn
- 小檗碱补充剂对成人血压的影响：一项GRADE评估的随机安慰剂对照试验的系统评价和Meta分析
- Title En
- The effect of berberine supplementation on blood pressure in adults: a GRADE-assessed systematic review and meta-analysis of randomized controlled-placebo trial studies
- Bilingual Status
- complete