Meta AnalysisID 6877
银杏叶提取物制剂治疗缺血性脑卒中的系统评价和网状Meta分析
CRD42023486259
The purpose of this network meta-analysis was to assess the efficacy and safety of Chinese patent medicines (CPMs) for patients with cardiovascular disease (CVD), such as stroke, transient ischemic attack (TIA) or corona
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Record Fields
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- Meta Analysis Id
- 6877
- Evidence Id
- 15435
- Core Evidence Id
- 15435
- Source Meta Analysis Id
- 6864
- Herb2 Meta Analysis Id
- HBMA006864
- Crd Id
- CRD42023486259
- Title
- Systematic review and network meta-analysis of Ginkgo biloba extract preparations for ischemic stroke
- Review Question
- The purpose of this network meta-analysis was to assess the efficacy and safety of Chinese patent medicines (CPMs) for patients with cardiovascular disease (CVD), such as stroke, transient ischemic attack (TIA) or coronary heart disease (CHD).
- Study Type Included
- Randomized controlled trials (RCTs).
- Condition Being Studied
- Globally, one third, or 17.9 million, of total annual deaths are attributable to cardiovascular disease (CVD). The incidence of cardiovascular disease has declined since the middle of the last century, but less so in women than in men. CVD, such as stroke, transient ischemic attack, and coronary heart disease, share common (traditional) risk factors, including hypertension, hyperglycemia, hyperlipidemia, hyperuricemia, and obesity. Western medicines, such as hypotensive, hypoglycemic, lipid-lowering, and uric acid-lowering therapies, are adopted as treatment for symptoms. Chinese patent medicines (CPMs), are now used as an adjuvant therapy for treating CVD by promoting host metabolism, alleviating glucose and lipid variability and delaying diabetes-related macrovascular complications. Encouragingly, recent studies introduced that CPMs combined with western medicines had synergistic effects to improve glucose and lipid metabolism and reduce associated adverse reactions through multiple pathways. Accordingly, this network meta-analysis and systematic review is to synthesize satisfying researches to assess and analyze the efficacy and safety of CPMs for patients with CVD.
- Participant
- Patients with CVD.
- Animal
- Human Disease Modelled
- Intervention
- CPMs alone or combined with western medicines, or usual care, etc.
- Comparator Control
- Western medicines, such as aspirin or edaravone injection and more , usual care, or placebo, etc.
- Main Outcome
- Clinical efficacy rate (CER); adverse reaction rate (ADRR), etc. Measures of effect All outcomes presented as binary variables should be expressed as active and total numbers.
- Outcome Measure
- Additional Outcome
- None. Measures of effect None.
- Study Method
- Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Di ZHANG [email protected]
- Organisational Affiliation
- College of Pharmacy, Shandong University of Traditional Chinese Medicine
- Funding Source
- This work was supported by High Level Talent Cultivation Project of Traditional Chinese Medicine of Shandong Province (2023 No. 143 Letter, Health Commission of Shandong Province); Project of National Traditional Chinese Medicine Characteristic Technology Inheritance Talent (2023 No. 96 Human Education Letter, National Administration of Traditional Chinese Medicine); Project of National Famous and Old Traditional Chinese Medicine Expert ZHANG Hong-xing Inheritance Studio (2022 No. 75 Human Education Letter, National Administration of Traditional Chinese Medicine); Project of National Old Traditional Chinese Medicine Expert LIU Xiang-hong Inheritance (2022 No. 76 Human Education Letter, National Administration of Traditional Chinese Medicine); Natural Science Foundation of Shandong Province (ZR2019MH063); Project of Key Research and Development of Shandong Province (2019GNC21307); Project of Medical and Health Science and Technology Development of Shandong Province (2018WS199); and Project of Traditional Chinese Medicine Science and Technology Development of Shandong Province (2019-0208, 2019-0215, 2019-0220, 2019-0914, 2017-114, 2017-116, 2017-123, 2015-128, 2015-134).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- Chinese-Simplified, English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-11-24
- Registration Date
- 2023-12-05
- Anticipated Start Date
- 2023-06-01
- Anticipated Completion Date
- 2024-01-01
- Title Cn
- 银杏叶提取物制剂治疗缺血性脑卒中的系统评价和网状Meta分析
- Title En
- Systematic review and network meta-analysis of Ginkgo biloba extract preparations for ischemic stroke
- Bilingual Status
- complete