Meta AnalysisID 6800
5种中药注射剂对比利巴韦林治疗儿童急性上呼吸道感染的疗效：网状Meta分析与系统评价
CRD42023484099
Acute upper respiratory infection in children (AURI) is an upper respiratory tract infection caused by a variety of pathogens, and is one of the most common diseases in children. Traditional Chinese medicine (TCM) inject
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Record Fields
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- Meta Analysis Id
- 6800
- Evidence Id
- 15358
- Core Evidence Id
- 15358
- Source Meta Analysis Id
- 6788
- Herb2 Meta Analysis Id
- HBMA006788
- Crd Id
- CRD42023484099
- Title
- Efficacy of 5 different traditional Chinese medicine injection comparing Ribavirin in acute upper respiratory infection in children：A network meta analysis and systematic review.
- Review Question
- Acute upper respiratory infection in children (AURI) is an upper respiratory tract infection caused by a variety of pathogens, and is one of the most common diseases in children. Traditional Chinese medicine (TCM) injections are widely used in clinical practice. Their efficacy is unclear due to the lack of clear evidence. In this study, network meta-analysis (NMA) was used to evaluate the efficacy and safety of TCM injections in the treatment of AURI, and to provide a reference for clinical treatment.
- Study Type Included
- type of included studies: randomised controlled trials (RCTs)
- Condition Being Studied
- Acute upper respiratory infection in children (AURI) is a common respiratory disease in pediatric clinics, mainly characterized by rapid progression and severe fever. Because of the young age and immaturity of children, they are susceptible to viral and bacterial infections, and if the disease is not controlled in time, it is easy to develop into inflammatory lesions in neighboring organs and lymph nodes, and in severe cases, lung inflammation may occur further.Due to the unclear symptoms of children's complaints, rapid progression of the disease, and high complication rates, failure to diagnose early and provide symptomatic treatment may cause delays, which may adversely affect children's physical and mental health .The cause of AURI is mostly due to the invasion of nasopharynx by influenza virus, adenovirus and other viruses, and the clinical symptoms include headache, fever, sore throat, and runny nose, etc.. Due to differences in individual immunity, the disease varies in severity, and although it is a self-limiting disease with a good prognosis, it may cause complications and affect health if not treated in time.Western medicine treatment of this disease is based on antipyretic drugs and antibiotics, and Ribavirin is often used in clinical treatment, but the effect is poor.
- Participant
- the subjects of the study were those who met the requirements of the AURI diagnostic criteria—no limitations existed in age, sex, or nationality;
- Animal
- Human Disease Modelled
- Intervention
- Xiyanping injection(XYPI);Qingkailing injection(QKLI);Reduning injection(RDNI);Yanhuning injection(YHNI)Tanreqing injection(TRQI)
- Comparator Control
- Ribavirin injection
- Main Outcome
- Total Clinical Effectiveness Measures of effect RR
- Outcome Measure
- Additional Outcome
- Time to Relief of Cough;Anti-fever time, Time to Relief of Sore Throat ;Time to Relief of Runny Nose ;Time to Relief of Stuffy Nose Measures of effect SMD
- Study Method
- Network meta-analysis, Systematic review
- Keyword
- MeSH headings have not been applied to this record
- Contact
- Xinyi Guo [email protected]
- Organisational Affiliation
- Chengdu University of Traditional Chinese Medicine No.37, Shijiqiao Road, Jinniu District, Chengdu, Sichuan, China
- Funding Source
- None fundings Grant number(s) State the funder, grant or award number and the date of award None fundings
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-11-17
- Registration Date
- 2023-11-28
- Anticipated Start Date
- 2023-11-17
- Anticipated Completion Date
- 2023-12-17
- Title Cn
- 5种中药注射剂对比利巴韦林治疗儿童急性上呼吸道感染的疗效：网状Meta分析与系统评价
- Title En
- Efficacy of 5 different traditional Chinese medicine injection comparing Ribavirin in acute upper respiratory infection in children：A network meta analysis and systematic review.
- Bilingual Status
- complete