Meta AnalysisID 677
绝经后个体血清雌二醇与心血管事件：一项系统评价与Meta分析
CRD42022368235
What is the association between serum estradiol levels and cardiovascular mortality and adverse cardiovascular events in postmenopausal individuals?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 677
- Evidence Id
- 9235
- Core Evidence Id
- 9235
- Source Meta Analysis Id
- 656
- Herb2 Meta Analysis Id
- HBMA000656
- Crd Id
- CRD42022368235
- Title
- Serum estradiol and cardiovascular events in postmenopausal individuals: a systematic review and meta-analysis
- Review Question
- What is the association between serum estradiol levels and cardiovascular mortality and adverse cardiovascular events in postmenopausal individuals?
- Study Type Included
- Inclusion: Observational studies (cohort studies and case-control studies), RCT’s and quasi-RCT's. Exclusion: Case reports, case series, review articles, opinion pieces, books, commentaries, editorials, letters to the editor, or multimedia files (e.g., online videos, podcasts).
- Condition Being Studied
- Cardiovascular-related mortality, adverse cardiovascular events (i.e., myocardial infarction)
- Participant
- Inclusion criteria: healthy, postmenopausal individuals (defined as not having menses for a minimum of 12 months). Exclusion criteria: animal studies, individuals who had early menopause (<40 years of age), comorbid conditions (diabetes, hypertension, kidney disease, etc.).
- Animal
- Human Disease Modelled
- Intervention
- Serum estradiol levels.
- Comparator Control
- None.
- Main Outcome
- Our primary outcome is the prevalence of cardiovascular-related mortality. Our secondary outcome is prevalence of clinical cardiovascular events (myocardial infarction, ischemic or hemorrhagic stroke, hypertension, venous thromboembolism, coronary artery disease, heart failure, hospitalization). Measures of effect Prevalence proportion, incidence proportion, odds ratio, means/medians, 95% CI estimates at baseline and after periods of follow up (if applicable).
- Outcome Measure
- Additional Outcome
- None. Measures of effect Prevalence proportion, incidence proportion, odds ratio, means/medians, 95% CI estimates at baseline and after periods of follow up (if applicable).
- Study Method
- Systematic review
- Keyword
- Humans
- Contact
- Nabilah Gulamhusein [email protected]
- Organisational Affiliation
- Cumming School of Medicine, University of Calgary
- Funding Source
- None. Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> None.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Canada
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-10-27
- Registration Date
- 2022-11-06
- Anticipated Start Date
- 2022-11-14
- Anticipated Completion Date
- 2023-12-31
- Title Cn
- 绝经后个体血清雌二醇与心血管事件：一项系统评价与Meta分析
- Title En
- Serum estradiol and cardiovascular events in postmenopausal individuals: a systematic review and meta-analysis
- Bilingual Status
- complete