Meta AnalysisID 671

使用雌二醇、孕激素或避孕药作为促性腺激素释放激素拮抗剂方案预处理的效果

CRD42020187219

What is the effect of using estradiol, progestogen, or combined oral contraceptive pill as pretreatment for IVF GnRH antagonist cycles?

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Record Fields

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Meta Analysis Id
671
Evidence Id
9229
Core Evidence Id
9229
Source Meta Analysis Id
650
Herb2 Meta Analysis Id
HBMA000650
Crd Id
CRD42020187219
Title
The effect of using of estradiol, progestogen, or contraceptive pill as pretreatment for GnRH antagonist cycles
Review Question
What is the effect of using estradiol, progestogen, or combined oral contraceptive pill as pretreatment for IVF GnRH antagonist cycles?
Study Type Included
We include randomised controlled trials and observational studies.
Condition Being Studied
We would like to the study the effect of using of estradiol, progestogen, or contraceptive pill as pretreatment for GnRH antagonist cycles in relationship to live birth rate, miscarriage rate, stillbirth rate, cycle scheduling, OHSS rate, number of oocytes retrieved and ovarian cyst formation.
Participant
Women treated with estradiol, progestogen, or contraceptive pill as pretreatment for specifically GnRH antagonist IVF cycles
Animal
Human Disease Modelled
Intervention
The intervention is the use of estradiol, progestogen, or combined oral contractive pill as pretreatment prior to starting IVF antagonist cycle.
Comparator Control
The control is women not using pretreatment or using alternative pretreatment prior to starting IVF antagonist cycle.
Main Outcome
Pregnancy outcomes - live birth >24 weeks gestation Measures of effect Relative risks for randomised controlled trials Odds ratios for observational studies
Outcome Measure
Additional Outcome
Pregnancy loss - miscarriage (pregnancy loss <24 weeks gestation), stillbirth (pregnancy loss >24 weeks gestation) Effective cycle scheduling OHSS rate Number of oocytes retrieved Ovarian cyst formation Measures of effect Relative risks for randomised controlled trials Odds ratios for observational studies
Study Method
Meta-analysis, Systematic review
Keyword
Contraceptive Agents; Contraceptive Devices; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Progestins
Contact
Jane Ding [email protected]
Organisational Affiliation
The Centre for Reproductive Medicine, St Bartholomew’s Hospital
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
England
Review Stage
Review Ongoing
First Submission Date
2020-07-12
Registration Date
2020-10-13
Anticipated Start Date
2020-05-19
Anticipated Completion Date
2021-05-01
Title Cn
使用雌二醇、孕激素或避孕药作为促性腺激素释放激素拮抗剂方案预处理的效果
Title En
The effect of using of estradiol, progestogen, or contraceptive pill as pretreatment for GnRH antagonist cycles
Bilingual Status
complete