Meta AnalysisID 6670
舒肝解郁汤治疗冠心病伴抑郁症的疗效与安全性评价
CRD42022353121
本研究系统评价或描述性分析了舒干洁玉汤在冠心病合并抑郁症治疗中的临床疗效及应用。
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Record Fields
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- Meta Analysis Id
- 6670
- Evidence Id
- 15228
- Core Evidence Id
- 15228
- Source Meta Analysis Id
- 6652
- Herb2 Meta Analysis Id
- HBMA006652
- Crd Id
- CRD42022353121
- Title
- Efficacy and safety evaluation of Shugan Jieyu Decoction in treating coronary heart disease with depression
- Review Question
- 本研究系统评价或描述性分析了舒干洁玉汤在冠心病合并抑郁症治疗中的临床疗效及应用。
- Study Type Included
- We only included the Chinese and English clinical randomized controlled trials published from January 2012 to January 2022.
- Condition Being Studied
- Coronary heart disease and depression are the main problems that endanger human health worldwide. Epidemiological studies have shown that depression is a psychological risk factor for coronary heart disease, and nearly 30% of patients with affective disorders have coronary heart disease .The strong association between depression and coronary artery disease has led many to recommend universal screening for depression in all patients with coronary artery disease and endorsed by the American Psychiatric Association . There is a bidirectional causal relationship between psychological and somatic factors and the pathogenesis of coronary artery disease.
- Participant
- Patients with coronary heart disease and depression
- Animal
- Human Disease Modelled
- Intervention
- The experimental group was treated with Shugan Jieyu Decoction, and the control group was treated with conventional western medicine. The experimental group was treated with conventional western medicine + Shugan Jieyu Decoction, and the control group was treated with conventional western medicine.
- Comparator Control
- Conventional western drugs are aspirin, nitrates, beta-blockers, and statins. Clopidogrel is given in patients with unstable coronary artery disease, and nitroglycerin 0.5 mg is included during angina attacks. The batch, dose, administration time, and course of treatment of the two groups were not limited.
- Main Outcome
- The total effective rate of angina pectoris and depression improved; Total effective rate = (total cases - invalid cases) /total cases ×100%.
- Outcome Measure
- Additional Outcome
- SDS score, HAMD score, and CPR and HCY test index scores.
- Study Method
- Systematic review
- Keyword
- Coronary Disease; Depression; Depressive Disorder; Humans; Phytotherapy
- Contact
- LI Zhenzhen [email protected]
- Organisational Affiliation
- shandong university of tranditional Chinese medicine
- Funding Source
- his work was supported by the National Natural Science Foundation of China (82074293) and the Key Project of the Shandong Provincial Natural Science Foundation (ZR2020ZD17). Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> 82074293 zr2020ZD17
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-08-12
- Registration Date
- 2022-08-22
- Anticipated Start Date
- 2022-06-16
- Anticipated Completion Date
- 2022-09-10
- Title Cn
- 舒肝解郁汤治疗冠心病伴抑郁症的疗效与安全性评价
- Title En
- Efficacy and safety evaluation of Shugan Jieyu Decoction in treating coronary heart disease with depression
- Bilingual Status
- complete