Meta AnalysisID 6668

舒肝解郁胶囊治疗女性抑郁症的疗效与安全性:系统评价与Meta分析

CRD42021252366

The aim of the research of randomized controlled trials is to evaluate the efficacy and safety of the Shugan Jieyu capsule for depressive disorders in women.

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Record Fields

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Meta Analysis Id
6668
Evidence Id
15226
Core Evidence Id
15226
Source Meta Analysis Id
6650
Herb2 Meta Analysis Id
HBMA006650
Crd Id
CRD42021252366
Title
Efficacy and safety of Shugan Jieyu capsule on treating female depression: a systematic review and meta-analysis
Review Question
The aim of the research of randomized controlled trials is to evaluate the efficacy and safety of the Shugan Jieyu capsule for depressive disorders in women.
Study Type Included
Only randomised controlled trials will be included.
Condition Being Studied
Depression. Depressive disorders in women.
Participant
Inclusion criteria: Women with a diagnosis of depressive disorders according to the criteria of the International Classification of Diseases 10 (ICD-10). Or Women with a diagnosis of depressive disorders according to the criteria of the Diagnostic and statistical manual of mental disorders(DSM-5). Exclusion criteria: - Participants with psychotic symptoms - Health comorbidities such as stroke, hypothyroidism, insomnia, heart failure, irritable bowel -Suicidal tendency, alcohol and drug dependence -research with obvious and uncorrectable errors or plagiarism.
Animal
Human Disease Modelled
Intervention
1.Shugan Jieyu capsules alone 2.Shugan Jieyu capsules plus placebo or antidepressant monotherapy
Comparator Control
1. Placebo or antidepressant 2. Antidepressant plus placebo or antidepressant monotherapy
Main Outcome
1.HAMD: Change in depression score from baseline to the last available follow-up, measured using the Hamilton Depression Scale 2. MADRS: Change in depression score from baseline to the last available follow-up, measured using the Montgomery-Asberg Depression Rating Scale Measures of effect Before and after treatment, the period of treatment is evaluated.
Outcome Measure
Additional Outcome
1. HAMA: Change in anxiety score from baseline to the last available follow-up, measured using the Hamilton Anxiety Scale 2.SDS: Change in depression score from baseline to the last available follow-up, measured using the Self-rating depression scale 3. BDI: Change in depression score from baseline to the last available follow-up, measured using the Beck Depression Inventory 4.Adverse reaction rate. Measures of effect Standardized mean difference, Relative risks.
Study Method
Meta-analysis, Systematic review
Keyword
Depression; Drugs, Chinese Herbal; Female; Humans; Phytotherapy
Contact
Li Junnan [email protected]
Organisational Affiliation
Beijing University of Chinese Medicine http://english.bucm.edu.cn/
Funding Source
National Natural Science Foundation of China, number:81874422;81573843
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2021-06-12
Registration Date
2021-07-13
Anticipated Start Date
2021-03-28
Anticipated Completion Date
2021-12-15
Title Cn
舒肝解郁胶囊治疗女性抑郁症的疗效与安全性:系统评价与Meta分析
Title En
Efficacy and safety of Shugan Jieyu capsule on treating female depression: a systematic review and meta-analysis
Bilingual Status
complete