Meta AnalysisID 6616

紫龙金片联合化疗治疗非小细胞肺癌的效果:随机对照试验的系统评价与Meta分析

CRD42020162177

chemotherapy often causes many serve adverse reactions, such as myelosuppression, nausea and vomiting. Patients with NSCLC may be discouraged from chemotherapy because of them.

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Record Fields

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Meta Analysis Id
6616
Evidence Id
15174
Core Evidence Id
15174
Source Meta Analysis Id
6596
Herb2 Meta Analysis Id
HBMA006596
Crd Id
CRD42020162177
Title
The Effect of Zilongjin Tablets combined with chemotherapy in the treatment of non-small cell lung cancer: A systematic review and meta-analysis of randomized controlled trials
Review Question
chemotherapy often causes many serve adverse reactions, such as myelosuppression, nausea and vomiting. Patients with NSCLC may be discouraged from chemotherapy because of them.
Study Type Included
All patients in control group were mainly treated with chemotherapy whose regimen was not limited. The patients in the experimental group were treated with chemotherapy combined with Zilongjin tablets whose intervention must be guaranteed as the only variable.
Condition Being Studied
In the classification of lung cancer, non-small cell lung cancer (NSCLC) accounts for about 85%. Because most patients are diagnosed with NSCLC in advanced stage, platinum-based chemotherapy is the main treatment . However, fatally, chemotherapy often causes many serve adverse reactions, such as myelosuppression, nausea and vomiting. Patients with NSCLC may be discouraged from chemotherapy because of them. There is no doubt that something should be found to solve this problem.
Participant
Participants were selected with the pathological diagnosis which was belong to NSCLC without limitations on region, age, and gender.
Animal
Human Disease Modelled
Intervention
Zilongjin Tablets combined with chemotherapy
Comparator Control
chemotherapy
Main Outcome
1.the solid tumor effect, Measures of effect ORR and DCR according to WHO or RECIST standard
Outcome Measure
Additional Outcome
1.the improvement in the quality of life, 2.the reduction in adverse effects rate Measures of effect 1.KPS 2.adverse effects according to WHO standard.
Study Method
Meta-analysis, Systematic review
Keyword
Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Randomized Controlled Trials as Topic; Tablets; zilongjin
Contact
Jixin Chen [email protected]
Organisational Affiliation
Funding Source
the National Natural Science Foundation of China (81974543)
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2019-12-12
Registration Date
2020-04-28
Anticipated Start Date
2019-12-08
Anticipated Completion Date
2020-01-10
Title Cn
紫龙金片联合化疗治疗非小细胞肺癌的效果:随机对照试验的系统评价与Meta分析
Title En
The Effect of Zilongjin Tablets combined with chemotherapy in the treatment of non-small cell lung cancer: A systematic review and meta-analysis of randomized controlled trials
Bilingual Status
complete