Meta AnalysisID 6409

银杏叶制剂(口服和注射)治疗不稳定型心绞痛:一项系统评价和网状Meta分析

CRD42022361487

What are the differences in the efficacy and safety of various ginkgo leaf preparations in the treatment of unstable angina pectoris?

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Record Fields

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Meta Analysis Id
6409
Evidence Id
14967
Core Evidence Id
14967
Source Meta Analysis Id
6393
Herb2 Meta Analysis Id
HBMA006393
Crd Id
CRD42022361487
Title
Ginkgo leaf preparations (oral and injectable) in the treatment of unstable angina pectoris: A systematic review and network Meta-analysis
Review Question
What are the differences in the efficacy and safety of various ginkgo leaf preparations in the treatment of unstable angina pectoris?
Study Type Included
We will include randomized controlled trials to assess the efficacy and safety of the treatments.
Condition Being Studied
Unstable angina pectoris.
Participant
Inclusion: Adults with unstable angina pectoris (as diagnosed using any recognised diagnostic criteria). Exclusion: Pregnant and lactating women, and participants had other serious diseases, such as acute myocardial infarction, severe heart failure, disturbance of blood coagulation, or disease of the liver or kidneys.
Animal
Human Disease Modelled
Intervention
Ginkgo biloba preparations: Ginkgo leaf tablet, Ginkgo leaf dispersible tablet, Ginkgo leaf capsule, Ginkgo leaf soft capsule, Ginkgo dropping pill, Ginkgo leaf granule, Ginkgo leaf tincture, Ginkgo leaf extract drop, Ginkgo leaf oral liquid, Yinxing Mihuan oral solution, Xingling dropping pill, Ginkgo ketone ester dropping pill, Ginkgo ketone ester tablet, Ginkgo ketone ester granule, Ginkgo ketone ester dispersible tablet, Ginkgo leaf extract injection, Shuxuening injection and diterpene ginkgolides meglumine injection.
Comparator Control
Routine treatment of unstable angina pectoris, including antiplatelet agents, nitroglycerine, beta-blockers, long-acting calcium-channel blockers, and angiotensin-converting-enzyme inhibitors, etc.
Main Outcome
Total efficacy against UAP (significantly effective+effective) and total effectiveness of electrocardiography.
Outcome Measure
Additional Outcome
Frequency of acute angina attack, duration of angina, clinical symptom response rate, hs-CRP level, vascular endothelial cell function index and cardiac function index.
Study Method
Intervention, Meta-analysis, Network meta-analysis, Systematic review
Keyword
Angina Pectoris; Angina, Unstable; Ginkgo biloba; Humans; Network Meta-Analysis; Plant Leaves
Contact
Yaoyuan Liu [email protected]
Organisational Affiliation
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Funding Source
None.
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-09-23
Registration Date
2022-10-04
Anticipated Start Date
2022-11-01
Anticipated Completion Date
2023-02-01
Title Cn
银杏叶制剂(口服和注射)治疗不稳定型心绞痛:一项系统评价和网状Meta分析
Title En
Ginkgo leaf preparations (oral and injectable) in the treatment of unstable angina pectoris: A systematic review and network Meta-analysis
Bilingual Status
complete