Meta AnalysisID 6339
清开灵注射液治疗社区获得性肺炎的疗效：一项系统评价与Meta分析
CRD42021272528
Many studies have shown that Qingkailing Injection combined with antibiotics is effective in the treatment of CAP, but there is a lack of systematic review and meta-analysis.
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Formula: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 6339
- Evidence Id
- 14897
- Core Evidence Id
- 14897
- Source Meta Analysis Id
- 6323
- Herb2 Meta Analysis Id
- HBMA006323
- Crd Id
- CRD42021272528
- Title
- Efficacy of Qingkailing injection for community acquired pneumonia(CAP): A Systematic Review and Meta-Analysis
- Review Question
- Many studies have shown that Qingkailing Injection combined with antibiotics is effective in the treatment of CAP, but there is a lack of systematic review and meta-analysis.
- Study Type Included
- Inclusion Criteria (1) type: Randomized controlled trial (RCT), patients were randomly enrolled, allocation of concealment or blind method was not required. (2) Subjects: Included patients meet clear CAP diagnostic criteria and exclusion criteria. (3) Interventions: The experimental group was treated with Qingkailing Injection combined with antibiotics (unlimited types, dosage, usage and course of treatment), and the control group was treated with the same antibiotics as the experimental group. Exclusion: (1) Different reports or repeated publications of the same study. (2) Non-randomized controlled trial (3) Types of antibiotics is unclear. (4) Research on incomplete or unable to extract data.
- Condition Being Studied
- Community acquired pneumonia is a common infectious disease threatening human health. Its pathogen composition and drug resistance characteristics vary significantly in different countries and regions, and continue to change with the passage of time, and the incidence, treatment failure rate and case fatality rate show a linear upward trend with the increase of age. In recent years, with the aging of the population and the abuse of antibiotics, the treatment of community-acquired pneumonia is facing a new dilemma.
- Participant
- Patients with community acquired pneumonia
- Animal
- Human Disease Modelled
- Intervention
- Qingkailing Injection combined with antibiotics(unlimited types, dosage, usage and course of treatment).
- Comparator Control
- The control group was treated with the same antibiotics as the experimental group.
- Main Outcome
- Recovery rate, Days of using antibiotics Measures of effect The criteria for evaluating the curative effect refer to “The Guiding principles for Clinical Research of New drugs of traditional Chinese Medicine”, recovery rate use Risk Ratios, Days of using antibiotics use Mean Difference.
- Outcome Measure
- Additional Outcome
- Time to resolution of symptomatic illness (cough, expectoration, lung rale, body temperature), Blood markers (WBC, PCT, CRP) and adverse events. Measures of effect Time to resolution of symptomatic illness use Mean Difference, Laboratory indicators after treatment use Mean Difference, adverse events use Risk Ratios.
- Study Method
- Intervention, Systematic review
- Keyword
- Community-Acquired Infections; Humans; Pneumonia; Qingkailing
- Contact
- Linqiong Zhou [email protected]
- Organisational Affiliation
- Henan University of Traditional Chinese Medicine
- Funding Source
- Young Qihuang scholar of National Administration of Traditional Chinese Medicine, Central Plains Talents Program -- Leading Talents in Basic Research of Central Plains, Top Talents of Traditional Chinese Medicine in Henan Provincial Traditional Chinese Medicine Inheritance and Innovation Talent Project
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-08-09
- Registration Date
- 2021-09-10
- Anticipated Start Date
- 2021-08-01
- Anticipated Completion Date
- 2021-09-15
- Title Cn
- 清开灵注射液治疗社区获得性肺炎的疗效：一项系统评价与Meta分析
- Title En
- Efficacy of Qingkailing injection for community acquired pneumonia(CAP): A Systematic Review and Meta-Analysis
- Bilingual Status
- complete