Meta AnalysisID 6338
清开灵注射液治疗流行性感冒患者的系统评价与随机对照试验的Meta分析
CRD42020213958
The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of qingkailing injection for influenza.
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Record Fields
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- Meta Analysis Id
- 6338
- Evidence Id
- 14896
- Core Evidence Id
- 14896
- Source Meta Analysis Id
- 6322
- Herb2 Meta Analysis Id
- HBMA006322
- Crd Id
- CRD42020213958
- Title
- Qingkailing injection for Patients with Influenza: A Systematic Review and Meta-analysis of Randomized Controlled Trials
- Review Question
- The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of qingkailing injection for influenza.
- Study Type Included
- Randomized controlled trials (RCTs) will be included.
- Condition Being Studied
- Influenza is an acute respiratory infectious disease, mainly caused by influenza virus. It is mainly transmitted by droplets in the air, human to human contact or contact with contaminated materials. The typical clinical manifestations are sudden high fever, general pain and respiratory symptoms. Influenza viruses are mainly divided into three types, named as type A, type B and type C respectively. Every year during the flu season, a large number of people will be infected with influenza, causing a huge health and financial burden, and many people die of influenza or other diseases caused by influenza.At present, there has been a certain resistance to influenza. Traditional Chinese medicine may be used as a candidate drug for combined treatment. Qingkailing injection has been used in clinic for many years and is often used in the treatment of influenza patients. This study aims to explore its effectiveness and safety.
- Participant
- People with influenza (as diagnosed by a clinician, or using any recognized diagnostic criteria) will be included.People who cannot cooperate with influenza or mental illness will be excluded.
- Animal
- Human Disease Modelled
- Intervention
- Application of Qingkailing injection combined with other antiviral drugs in the treatment of influenza is an intervention measure.
- Comparator Control
- Treatment of influenza with antiviral drugs alone.
- Main Outcome
- Disappearance time of clinical symptoms Measures of effect We used the random effects model to calculate the 95% confi dence interval (CI) and odds ratio (OR) or mean difference (MD) of outcomes due to the inclusion criteria,intervention and comparisons not being exactly the same.
- Outcome Measure
- Additional Outcome
- Negative time of influenza virus nucleic acid detection Measures of effect We used the random effects model to calculate the 95% confi dence interval (CI) and odds ratio (OR) or mean difference (MD) of outcomes due to the inclusion criteria, intervention and comparisons not being exactly the same.
- Study Method
- Systematic review
- Keyword
- Drugs, Chinese Herbal; Humans; Influenza, Human; Qingkailing; Randomized Controlled Trials as Topic
- Contact
- Qingquan Liu [email protected]
- Organisational Affiliation
- Capital Medical University, China
- Funding Source
- There is no financial support at present
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-10-12
- Registration Date
- 2020-11-12
- Anticipated Start Date
- 2020-09-15
- Anticipated Completion Date
- 2021-02-28
- Title Cn
- 清开灵注射液治疗流行性感冒患者的系统评价与随机对照试验的Meta分析
- Title En
- Qingkailing injection for Patients with Influenza: A Systematic Review and Meta-analysis of Randomized Controlled Trials
- Bilingual Status
- complete