Meta AnalysisID 6240

津力达颗粒联合二甲双胍治疗2型糖尿病:一项更新版系统评价和Meta分析

CRD42022312715

The purpose of this meta-analysis is to evaluate the efficacy and safety of jinlida granule combined with metformin in the treatment of type 2 diabetes, and to provide clinical evidence guidance.

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Record Fields

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Meta Analysis Id
6240
Evidence Id
14798
Core Evidence Id
14798
Source Meta Analysis Id
6223
Herb2 Meta Analysis Id
HBMA006223
Crd Id
CRD42022312715
Title
Jinlida granules combined with metformin for type 2 diabetes: an updated systematic review and meta-analysis
Review Question
The purpose of this meta-analysis is to evaluate the efficacy and safety of jinlida granule combined with metformin in the treatment of type 2 diabetes, and to provide clinical evidence guidance.
Study Type Included
We include only published randomized controlled trials, ruled out any other types of articles.
Condition Being Studied
The Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes (2020 edition) pointed out that for type 2 diabetes (T2DM) with deficiency of both qi and yin, on the basis of the application of hypoglycemic drugs such as metformin, Jinlida granules can be added. In recent years, the number of randomized controlled trials in Jinlida granules combination with metformin for the treatment of type 2 diabetes continues to increase, therefore, it is necessary to conduct an updated meta-analysis to provide a more accurate evidence-based basis for clinical practice.
Participant
Participants were clearly diagnosed with type 2 diabetes, randomized controlled trials with type 2 diabetes as the primary disease to be treatedand, and the diagnostic criteria included: WHO 1999 Diagnostic Criteria and Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes (2020 Edition).
Animal
Human Disease Modelled
Intervention
The intervention group was oral jinlida granule plus metformin, and other types of hypoglycemic drugs were excluded.
Comparator Control
The control group received metformin orally.
Main Outcome
glycated hemoglobin(HbA1c)
Outcome Measure
Additional Outcome
1) fasting blood glucose(FBG); 2) 2 hours postprandial blood glucose(2hPG); 3) time in range(TIR); 4) adverse events(AEs)
Study Method
Meta-analysis, Systematic review
Keyword
Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Humans; Hypoglycemic Agents; Metformin; jinlida
Contact
Fengya Zhu [email protected]
Organisational Affiliation
Chengdu University of TCM
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-02-23
Registration Date
2022-03-26
Anticipated Start Date
2022-03-01
Anticipated Completion Date
2022-08-01
Title Cn
津力达颗粒联合二甲双胍治疗2型糖尿病:一项更新版系统评价和Meta分析
Title En
Jinlida granules combined with metformin for type 2 diabetes: an updated systematic review and meta-analysis
Bilingual Status
complete