Meta AnalysisID 6239
金乌骨通胶囊治疗膝骨关节炎的疗效与安全性：一项随机对照试验的Meta分析
CRD42022299576
The purpose of this study is to systematically evaluate the clinical efficacy and safety of JWGT in the treatment of KOA.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 6239
- Evidence Id
- 14797
- Core Evidence Id
- 14797
- Source Meta Analysis Id
- 6222
- Herb2 Meta Analysis Id
- HBMA006222
- Crd Id
- CRD42022299576
- Title
- The Efficacy and Safety of Jinwu Gutong Capsule in the Treatment of Knee Osteoarthritis: A Meta-analysis of Randomized Controlled Trials
- Review Question
- The purpose of this study is to systematically evaluate the clinical efficacy and safety of JWGT in the treatment of KOA.
- Study Type Included
- The type of study must be a randomized controlled trial.
- Condition Being Studied
- Knee osteoarthritis (KOA) is a chronic joint disease that is influenced by many factors and eventually leads to an imbalance in the degradation and synthesis of chondrocytes, extracellular matrix and subchondral bone . With the acceleration of population ageing and the increase in the obese population, the prevalence of KOA has nearly doubled compared with the prevalence in the middle of the 20th century, which was approximately 16%.
- Participant
- All the included patients had KOA, and there was clear diagnostic criteria for KOA in the article.
- Animal
- Human Disease Modelled
- Intervention
- The experimental group was treated with JWGT as an intervention measure or JWGT in addition to the treatment provided to the control group.
- Comparator Control
- The control group was treated with conventional Western medicine treatments, such as GS, NSAIDs, HA, etc.
- Main Outcome
- effective rate, VAS score, adverse reactions
- Outcome Measure
- Additional Outcome
- KSS score, WOMAC score, IL-6, TNF-α
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Humans; Injections, Intra-Articular; Knee Joint; Osteoarthritis, Knee; Randomized Controlled Trials as Topic
- Contact
- Jinlong Zhao [email protected]
- Organisational Affiliation
- Guangzhou University of Traditional Chinese Medicine
- Funding Source
- This work was supported by the National Natural Science Foundation of China (No. 82004386, No. 81873314, No.82004383, No. 81974574), the Project of Administration of Traditional Chinese Medicine of Guangdong Province (No.20201129), the Project of Guangdong Provincial Department of Finance (No.[2018]8), the Medical Science Research Foundation of Guangdong Province (No. B2019091), the Key scientific research platforms and research projects of universities in Guangdong Province (No. 2018KQNCX041), the Science and Technology Planning Project of Guangdong Province (No. 2020A1414050050) and the Science and Technology Research Project of Guangdong Provincial Hospital of Chinese Medicine (No.YN2019ML08, YN2015MS15).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-12-21
- Registration Date
- 2022-01-20
- Anticipated Start Date
- 2021-12-15
- Anticipated Completion Date
- 2022-01-31
- Title Cn
- 金乌骨通胶囊治疗膝骨关节炎的疗效与安全性：一项随机对照试验的Meta分析
- Title En
- The Efficacy and Safety of Jinwu Gutong Capsule in the Treatment of Knee Osteoarthritis: A Meta-analysis of Randomized Controlled Trials
- Bilingual Status
- complete