Meta AnalysisID 6187

荷丹片治疗高脂血症的临床疗效与安全性:Meta分析与系统评价

CRD42019145375

To evaluate the efficacy and safety of Hedan Tablet in patients with hyperlipidemia

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Record Fields

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Meta Analysis Id
6187
Evidence Id
14745
Core Evidence Id
14745
Source Meta Analysis Id
6166
Herb2 Meta Analysis Id
HBMA006166
Crd Id
CRD42019145375
Title
Clinical efficacy and safety of hedan tablets for the treatment of hyperlipidemia: a meta-analysis and systematic review
Review Question
To evaluate the efficacy and safety of Hedan Tablet in patients with hyperlipidemia
Study Type Included
Randomized controlled trials
Condition Being Studied
Hyperlipidemia is a major risk factor for cardiovascular and cerebrovascular diseases. Hyperlipidemia could induce atherosclerosis, leading to coronary heart disease, stroke, and myocardial infarction, increasing the incidence and mortality rate of cardio-cerebrovascular diseases.
Participant
Participants, adult patients (18 years of age and older) with HL whose blood lipids are abnormal for 2 consecutive tests after stopping lipid regulating agent and diet therapy 2 to 4 weeks later will be included. HL should be confirmed according to the standard diagnostic criteria including the “Guidelines for the prevention and treatment of dyslipidemia in Chinese adults (2016). <h1>Intervention(s), exposure(s)
Animal
Human Disease Modelled
Intervention
The therapy used Hedan tablet by oral administration. The interventions used in the control group include placebo, blank control, and conventional western medicine (such as stains). The administration time for both the control and experimental groups must not be less than 4 weeks.
Comparator Control
Control group: placebo, blank control, and conventional western medicine (such as stains).
Main Outcome
The primary outcome indicators are determined according to the Guiding Principles for Clinical Research of Drugs
Outcome Measure
Additional Outcome
The secondary outcome includes Serum TC, TG, LDL-C, HDL-C, apolipoprotein A (apo A), apo B
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Drugs, Chinese Herbal; Humans; Hyperlipidemias; Tablets; Treatment Outcome; hedan
Contact
Organisational Affiliation
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
First Submission Date
Registration Date
2019-10-31
Anticipated Start Date
2019-07-20
Anticipated Completion Date
2020-07-01
Title Cn
荷丹片治疗高脂血症的临床疗效与安全性:Meta分析与系统评价
Title En
Clinical efficacy and safety of hedan tablets for the treatment of hyperlipidemia: a meta-analysis and systematic review
Bilingual Status
complete