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中药当归四逆汤治疗膝骨关节炎的疗效和安全性:系统评价和Meta分析的研究方案

CRD42022361901

The aim of this review is to evaluate the effectiveness and safety of Danggui Sini decoction for knee osteoarthritis.

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At a Glance

Curated fields selected for quick interpretation of this Meta Analysis record.

CRD ID
CRD42022361901
Country
China
Review Stage
Review Ongoing

Review Identity

Review registration and scope.

CRD ID
CRD42022361901
Review Stage
Review Ongoing
Country
China
Language
English

Review Question

Population, intervention, comparator, and outcomes.

Review Question
The aim of this review is to evaluate the effectiveness and safety of Danggui Sini decoction for knee osteoarthritis.
Condition
Knee osteoarthritis(KOA) often causes joint pain, weakness and mobility disorders, which seriously affects people’s daily life and makes them unable to work and study normally.Traditional Chinese medicine prescription Danggui Sini Decoction(DGSND) has been widely used in clinical practice and achieved good results. But there is no high-level evidence to support this result. The aim of this study is to evaluate DGSND's efficacy and safety in the management of KOA.
Participant
Patients were diagnosed with knee osteoarthritis and the study belongs to a randomized controlled trial. Clinical results included clinical effectiveness and VAS. Experimental group must contain Danggui Sini decoction or modified Danggui Sini decoction.and control group was not limited except that. Otherwise, studies will be excluded if they cannot meet the inclusion criteria.
Intervention
Intervention of the experimental group is Danggui Sini decoction or modified Danggui Sini decoction. There are no restrictions on the way of administration, dosage and treatment period.
Comparator Control
The control group have other treatment methods different from Danggui Sini decoction or modified Danggui Sini decoction.
Main Outcome
The primary outcome is VAS.
Study Method
Meta-analysis, Systematic review

Registration Timeline

Submission and completion dates.

First Submission Date
2022-09-21
Registration Date
2022-10-02
Anticipated Start Date
2022-09-26
Anticipated Completion Date
2022-10-24