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当归四逆汤治疗糖尿病周围神经病变:随机对照试验的系统评价和Meta分析

CRD42020161585

Is Danggui Sini Decoction (DSD) beneficial for diabetic peripheral neuropathy (DPN)?

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At a Glance

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CRD ID
CRD42020161585
Country
China
Review Stage
Review Ongoing

Review Identity

Review registration and scope.

CRD ID
CRD42020161585
Review Stage
Review Ongoing
Country
China
Language
English

Review Question

Population, intervention, comparator, and outcomes.

Review Question
Is Danggui Sini Decoction (DSD) beneficial for diabetic peripheral neuropathy (DPN)?
Condition
Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes. It is hidden and has a significant impact on the quality of life of patients. Early identification and treatment of DPN is of great significance for patients' prognosis.
Participant
Adults with clinically diagnosed diabetic peripheral neuropathy.
Intervention
Danggui Sini Decoction (DSD) is a classical prescription described in Shanghan Zabing Lun, written by Zhang Zhongjing during the Han dynasty. Studies that used any type of DSD or a modified DSD are included, as are studies comparing the effects of DSD alone or combined with conventional medication (NSAID or OCP) to the effects of conventional medicine alone. A modified DSD is defined by practitioners as a DSD with no more than one of the original herbs, but which had the same action as the original DSD formula. We include all forms of this medication, such as extracts, tablets, capsules, pills, powders, and injections. Studies examining DSD combined with other herbal decoctions or with other types of therapy are excluded. Trials in which the DSD is used as an adjunct to conventional treatment, usual care, or standard care are included if the control group received the same concomitant treatment as the DSD group.
Comparator Control
No current/recent DSD use.
Main Outcome
Clinical efficacy. Measures of effect None
Study Method
Meta-analysis, Systematic review

Registration Timeline

Submission and completion dates.

First Submission Date
2019-12-08
Registration Date
2020-04-28
Anticipated Start Date
2019-12-18
Anticipated Completion Date
2020-05-23