Meta AnalysisID 5916

中国国家基本药物目录中中药注射剂治疗急性缺血性卒中有效性与安全性的系统评价与网状Meta分析

CRD42018079483

1.Can traditional Chinese medicine injections reduce the risk of a poor outcome (that is, being dependent on others in activities of daily living or death) several months after acute ischaemic stroke? 2.Can traditional C

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Record Fields

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Meta Analysis Id
5916
Evidence Id
14474
Core Evidence Id
14474
Source Meta Analysis Id
5898
Herb2 Meta Analysis Id
HBMA005898
Crd Id
CRD42018079483
Title
A systematic review and network meta-analysis for the efficacy and safety of traditional Chinese medicine injections for acute ischemic stroke on the national essential drugs list of China
Review Question
1.Can traditional Chinese medicine injections reduce the risk of a poor outcome (that is, being dependent on others in activities of daily living or death) several months after acute ischaemic stroke? 2.Can traditional Chinese medicine injections improve neurological function in patients with acute ischaemic stroke compared to placebo,no-treatment or conventional treatment? 3.If traditional Chinese medicine injections safe to use in patients with acute ischaemic stroke? 4.Compare the efficacy and safety with different traditional Chinese medicine injections.
Study Type Included
Randomized controlled trials (RCTs) will be included. Observational, cohort, case-control, case series, qualitative and laboratory studies, and uncontrolled trials will be excluded.
Condition Being Studied
Acute ischemic stroke is a major cause of death and disability worldwide. Most of acute ischemic strokes are due to blockage of an artery in the brain by a blood clot e.g. from the heart or neck arteries.
Participant
Patients with Acute ischemic stroke within 14 days of onset, diagnised by CT or MRI.
Animal
Human Disease Modelled
Intervention
Traditional Chinese Medicine Injections on the National Essential Drugs List of China, including Qingkailing injection, Mailuoning injection, Shenmai injection, Shengmai injection, Xueshuangtong injection, Xuesaitong injection, Danshen injection.
Comparator Control
Placebo,no-treatment and conventional treatment.
Main Outcome
1.Death or dependency. 2.Adverse Events.
Outcome Measure
Additional Outcome
1.Neurological Deficit Improvement After Treatment 2.Death From All Cause
Study Method
Meta-analysis, Network meta-analysis, Systematic review
Keyword
China; Drugs, Essential; Humans; Injections; Medicine, Chinese Traditional; Network Meta-Analysis; Stroke
Contact
He Sufei [email protected]
Organisational Affiliation
Tianjin University of Traditional Chinese Medicine http://www.tjutcm.edu.cn/
Funding Source
This study is supported by a project of National Natural Science Foundation of China (NO.81630106).
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
Country
China
Review Stage
Review Ongoing
First Submission Date
2018-02-01
Registration Date
2018-02-07
Anticipated Start Date
2018-01-01
Anticipated Completion Date
2018-03-06
Title Cn
中国国家基本药物目录中中药注射剂治疗急性缺血性卒中有效性与安全性的系统评价与网状Meta分析
Title En
A systematic review and network meta-analysis for the efficacy and safety of traditional Chinese medicine injections for acute ischemic stroke on the national essential drugs list of China
Bilingual Status
complete