Meta AnalysisID 5912

中草药方剂参苓白术散治疗消化性溃疡:系统评价与Meta分析

CRD42023407212

This study evaluates the efficacy and safety of the Chinese Herbal Formula Shen Ling Bai zhu San in symptomatic relief of Peptic ulcer.

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Record Fields

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Meta Analysis Id
5912
Evidence Id
14470
Core Evidence Id
14470
Source Meta Analysis Id
5895
Herb2 Meta Analysis Id
HBMA005895
Crd Id
CRD42023407212
Title
Chinese Herbal Formula Shen Ling Bai zhu San to treat Peptic ulcer:A Systematic Review and Meta-analysis
Review Question
This study evaluates the efficacy and safety of the Chinese Herbal Formula Shen Ling Bai zhu San in symptomatic relief of Peptic ulcer.
Study Type Included
Participants in the review included patients with peptic ulcers of all ages and no other severe organ or systemic disease. All the included patients were diagnosed with active peptic ulcer by gastroscopy. The exclusion criteria were as following:(1)Non-comparative studies (2)Studies that did not indicate a definite diagnosis by gastroscopy or pathological examination; (3) Studies with repeated publication or data duplication; (4) Experience summary, theoretical exposition and other review literature; (5) Pharmacology, pharmacokinetics, animal experiments, toxicological experiments and other non-clinical trials; (6) No valid data for analysis is reported.
Condition Being Studied
Peptic Ulcer (PU) usually refers to an ulcer that occurs when the mucous membrane of the gastrointestinal tract is digested by stomach acid and pepsin. It usually occurs in the stomach and duodenum, but can also occur in the lower esophagus, small intestine, anastomosis after gastrointestinal anastomosis, and gastric mucosa with ectopic location, such as Meckel diverticulum located in the intestine. Is the digestive system common disease and frequently-occurring disease.
Participant
Participants in the review included patients with peptic ulcers of all ages and no other severe organ or systemic disease. All the included patients were diagnosed with active peptic ulcer by gastroscopy. The exclusion criteria were as following:(1)Non-comparative studies (2)Studies that did not indicate a definite diagnosis by gastroscopy or pathological examination; (3) Studies with repeated publication or data duplication; (4) Experience summary, theoretical exposition and other review literature; (5) Pharmacology, pharmacokinetics, animal experiments, toxicological experiments and other non-clinical trials; (6) No valid data for analysis is reported.
Animal
Human Disease Modelled
Intervention
The patients with peptic ulcer were treated with the Chinese Herbal Formula Shen Ling Bai zhu San or combined with Western medicine.
Comparator Control
The patients with peptic ulcer were treated without the Chinese Herbal Formula Shen Ling Bai zhu San.
Main Outcome
Clinical efficacy (cure rate, total effective rate), recurrence rate, occurrence of adverse reactions.
Outcome Measure
Additional Outcome
Helicobacter pylori positive eradication rate, abdominal pain relief rate, abdominal distension relief rate.
Study Method
Meta-analysis, Systematic review
Keyword
Drugs, Chinese Herbal; Food, Formulated; Humans; Medicine, Chinese Traditional; Peptic Ulcer; shen ling bai zhu
Contact
Xiaofan Chen [email protected]
Organisational Affiliation
Jiangxi University Of Chinese Medicine
Funding Source
This work was supported by the National Natural Science Foundation of China [grant number 82260857]. Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> 82260857
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-03-20
Registration Date
2023-03-31
Anticipated Start Date
2022-10-31
Anticipated Completion Date
2023-06-01
Title Cn
中草药方剂参苓白术散治疗消化性溃疡:系统评价与Meta分析
Title En
Chinese Herbal Formula Shen Ling Bai zhu San to treat Peptic ulcer:A Systematic Review and Meta-analysis
Bilingual Status
complete